Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin

Indications

This combination is indicated in-

  • Vaginal trichomoniasis
  • Vaginal leucorrhoeas
  • Mixed vaginal infections (Fungal or Bacterial).

Pharmacology

Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.

Dosage And Administration

One suppository in the vagina at bedtime for 12 days or as directed by the physician.

Contraindications

Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.

Side Effects

Skin rash, urticaria may occur rarely.

Pregnancy And Lactation

Caution should be practiced in pregnancy and lactation.

Precautions And Warnings

Caution should be taken in case of renal impairment.

Therapeutic Class

Drugs used in Vaginal and Vulval condition

Storage Conditions

Store in a cool and dry place, away from light & children.