Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin
Indications
This combination is indicated in-
- Vaginal trichomoniasis
- Vaginal leucorrhoeas
- Mixed vaginal infections (Fungal or Bacterial).
Pharmacology
Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.
Dosage And Administration
One suppository in the vagina at bedtime for 12 days or as directed by the physician.
Contraindications
Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.
Side Effects
Skin rash, urticaria may occur rarely.
Pregnancy And Lactation
Caution should be practiced in pregnancy and lactation.
Precautions And Warnings
Caution should be taken in case of renal impairment.
Therapeutic Class
Drugs used in Vaginal and Vulval condition
Storage Conditions
Store in a cool and dry place, away from light & children.