Menaquinone-7

Indications

This capsule is indicated for the treatment and prevention of-

  • Osteoporosis
  • Coronary artery calcification
  • Rheumatoid arthritis

Pharmacology

Menaquinone-7 is a fat soluble vitamin which is also known as vitamin K2. Menaquinone-7 is an especial key isomer of vitamin K2 that is produced using Bacillus subtilis. Menaquinone-7 is the active trans-isomer of natural vitamin K2 with the highest bioavailability and longest half-life in blood. This makes Menaquinone-7 also available for tissues outside the liver, namely bones, arteries and soft tissues. It is a powerful cofactor in transporting excess calcium out of the arteries and depositing it into the bones thus prevents hardening of arteries. Menaquinone-7 is very essential for healthy bone and artery.

Dosage And Administration

Orally 1-2 capsules daily or as advised by the physician.

Interaction

Menaquinone-7 may alter the effect of warfarin. Concomitant use with orlistat may decrease the absorption of Menaquinone-7.

Contraindications

Contraindicated in patients with known hypersensitivity to Menaquinone-7. Use of Menaquinone-7 is contraindicated with warfarin.

Side Effects

Generally well tolerated in recommended dose. From a large number of clinical trials using dosages in excess of 40 mg/day, there were no reports of side effects associated with any type of hypercoagulable state.

Pregnancy And Lactation

Menaquinone-7 can be used during pregnancy. Use of Menaquinone-7 during pregnancy may help both mother and child in formation and maintaining proper bone health.

Therapeutic Class

Drugs for Osteoarthritis

Storage Conditions

Store at temperature below 30˚C, protect from light & moisture. Keep out of reach of children.