Dexpanthenol

Indications

Dexpanthenol is indicated in-

  • For prevention and treatment of diaper rash in infants.
  • For prevention and treatment of cracked or sore nipples in nursing women.
  • For prevention and treatment of chafed, cracked or split skin.
  • For treatment of light skin wounds and dry skin

Pharmacology

Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.

Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties

Dosage And Administration

Check with the doctor or pharmacist if you are unsure how to use Dexpanthenol.

The usual dosage is generally:

  • Diaper rash: Apply a thin layer on the baby’s bottom at every diaper change.
  • Nipples: Apply a thin layer on the nipples after each nursing session. Wash the nipples thoroughly before the next nursing session.
  • Dry/cracked skin or light wounds and chafed skin: Apply to the dry areas and/or to the wound up to 3 times a day.

Do not exceed the recommended dose, Do not swallow. This medicine is intended for external use only.

Side Effects

As with any medicine, use of Dexpanthenol may cause side effects in some users. Do not be alarmed by the list of side effects. You may not suffer from any of them. Discontinue use and refer to a doctor immediately in the event of: Allergic reaction and/or allergic skin reaction such as: atopic dermatitis, allergic dermatitis, pruritus, redness, rash, eczema, urticaria, local irritation or blistering. If a side effect occurs, worsens, or if you suffer from a side effect not mentioned in this leaflet, consult with the doctor.

Therapeutic Class

Miscellaneous topical agents

Storage Conditions

Do not store above 30 degree Celsius. Keep away from light and out of the reach of children.