Clotrimazole (Eye Oinment)
Indications
Clotrimazole Sterile Eye Ointment is indicated for the treatment of fungal keratitis due to filamentous fungi and Candida species.
Pharmacology
Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the production of ergosterol, which is an essential component of fungal cell membranes resulting in increased membrane permeability and leakage of essential constituents of the fungal cells.
Dosage And Administration
Eye ointment: It should be applied thinly and evenly to the conjunctival sac every 4 hours daily or as advised by a physician.
Contraindications
Clotrimazole ointment is contraindicated in individuals sensitive to its components.
Side Effects
Rarely patients may experience burning or irritation immediately after applying the ointment.
Pregnancy And Lactation
Pregnancy category B. There are no adequate and well-controlled studies in pregnant women during the first trimester of pregnancy. Clotrimazole should be used only if clearly indicated during the first trimester of pregnancy.
It is not known whether this drug is excreted in human milk, caution should be exercised when Clotrimazole is used by a nursing woman.
Precautions And Warnings
If irritation or sensitivity develops with the use of Clotrimazole ointment, treatment should be discontinued.
Therapeutic Class
Ophthalmic Anti-fungal Products
Use in special populations
Une in children: Safety and effectiveness in children have been established for Clotrimazole when used as indicated and in the recommended dosage.
