Cinchocaine + Hydrocortisone + Neomycin + Esculin

Indications

This is indicated for-

Internal and external hemorrhoids
Post-partum hemorrhoidal condition
Anal pruritus, peri-anal eczema, anal fissures and proctitis
Post-hemorrhoidectomy application to relieve pain and discomfort

Pharmacology

Cinchocaine is a local anesthetic which relieves severe pain and relaxes sphincteric spasm. Hydrocortisone acts as an anti-inflammatory and anti-pruritic agent and thereby eliminates itching and inflammation. Neomycin is a broad-spectrum antibiotic which eradicates most infections which may already be present or arise in lesions of the anorectal area. Esculin improves skin vasculature and is effective in management of cellulitis.

Dosage And Administration

Ointment: A small quantity of the ointment should be applied with finger in the painful pruritic area in the morning and evening and after each stool. For deep application nozzle should be attached to the tube and inserted to full extent and should be squeezed gently from the lower end while withdrawing.

Suppository: One suppository in the morning and one in the evening, and one after each stool.

Use in children: Not recommended for children.

Contraindications

Contraindicated in patients hypersensitive to any component of the product.

Side Effects

Side effects which have been reported for individual constituents may occur and appropriate precautions should be taken when using this preparation.

Pregnancy And Lactation

Use in pregnancy: The safe use of topical corticosteroids during pregnancy has not been fully established.

Precautions And Warnings

Like most of the steroids under certain circumstances hydrocortisone may be absorbed in sufficient amount to produce systemic effects. So, long term use should be avoided. Adrenal suppression may occur even without occlusion. When used for prolonged period striae may occur. Skin sensitisation may occur due to Neomycin. Absorption of the antibiotic from wound or inflamed skin may occur and this may affect the hearing irreversibly. Hence this preparation should not be given to extensively damaged skin.