Chlorhexidine Hydrochloride + Nystatin
Indications
It is used to treat skin infections caused by either fungi and/or bacteria, such as-
- Ringworm
- Athlete's foot and
- Infected nappy rash
Pharmacology
Nystatin is a fungistatic and fungicidal antibiotic primarily effective against Candida albicans. Chlorhexidine has activity against a wide range of bacteria. Nystatin is poorly absorbed from the gastrointestinal tract. It is not absorbed through the skin or mucous membranes when applied topically
Dosage And Administration
Route of administration: Topically
Child: Apply 2-3 times a day, continuing for 7 days after lesions have healed.
Adult: Apply 2-3 times a day, continuing for 7 days after lesions have healed. Or as directed by the physician.
Interaction
There are no known drug interactions.
Contraindications
Known hypersensitivity to the active substances, especially in those with a history of possible chlorhexidine-related allergic reactions.
Side Effects
Common side effects: Allergic skin reactions such as dermatitis, pruritus, erythema, eczema, rash and skin irritation. Rare side effects: Severe allergic reactions, leading to a drop in blood pressure and even to unconsciousness.
Pregnancy And Lactation
This cream should be administered with caution during the early months of pregnancy.
Precautions And Warnings
For external use only. Avoid contact with eyes. If sensitivity occurs, or if new infection appears, discontinue use and institute alternative therapy. This cream contains chlorhexidine. Chlorhexidine is known to induce hypersensitivity, including generalized allergic reactions and anaphylactic shock. This cream should not be administered to Anyone with a potential history of an allergic reaction to a chlorhexidine-containing compound.
Overdose Effects
This is poorly absorbed from the gastrointestinal tract. In the event of accidental oral ingestion, routine measures such as gastric lavage should be performed as soon as possible after ingestion.
Therapeutic Class
Chlorhexidine & Chloroxylenol preparations
Storage Conditions
Store below 30°C temperature & dry place, protected from light. Keep out of the reach of children.