Bacitracin Zinc + Polymyxin B Sulfate
Indications
This ophthalmic ointment is indicated in the treatment of bacterial infections of the eye and its adnexa including conjunctivitis, keratitis, corneal ulceration and ulcerative blepharitis. It may be applied to prevent ocular infection both pre and post operatively.
Pharmacology
This ophthalmic ointment is a sterile antimicrobial ointment for ophthalmic use, cointaining Polymixin-B sulphate and Bacitracin Zinc.
Polymixin-B sulphate and Becitracin Zinc are both bactericidal antibiotics, The former exerts its action by binding with the cellular membrane and the later by inhibiting bacterial cell wall development.
Dosage And Administration
Apply the ointment every 3 to 4 hourly for 7 to 10 days, depending on the severity of the infection or as directed by the physician.
Contraindications
Polytracin is contraindicated in those individuals who have shown hypersensitivity to Polymixin-B sulphate, Becitracin Zinc or to cross sensitizing substances.
Side Effects
Sometimes this ointment may be absorbed in the blood, but shows no blood related toxicity. Moreover Allergic reaction, eye irritation, eye redness, itching, swelling may occur.
Pregnancy And Lactation
Bacitracin Zinc: Pregnancy Category C
Polymyxin B Sulphate: Pregnancy Category B
Lactation: Undetermined
Therapeutic Class
Ophthalmic antibacterial drugs