Nitrofurazone

Indications

Nitrofurazone is indicated in the infectious conditions of the skin such as burns, wounds, ulcers, skin infections and skin grafting.

Pharmacology

Nitrofurazone is a broad spectrum topical antibacterial agent indicated for the treatment of mixed skin infections of superficial wounds and diseases of the skin.

Dosage And Administration

To be applied directly to the lesion or on gauze first; 2-3 times daily or as advised by the physician.

Contraindications

Nitrofurazone is contraindicated to patients with known sensitivity to Nitrofurazone. It is not advisable to use Nitrofurazone after the infection is cured. It should be used with caution in patients with known or suspected renal impairment.

Side Effects

Sensitization and generalized allergic skin reactions may be produced after few days of initial application. Cross sensitization to other Nitrofurazone derivatives may occur. Intolerance to Nitrofurazone necessitating withdrawal has been encountered.

Pregnancy And Lactation

Pregnancy category- B.

Precautions And Warnings

G6PD deficiency, renal impairment.

Therapeutic Class

Topical Antibiotic preparations