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Indications

Aluminium Oxide & Magnesium Trisilicate is indicated in Heartburn, Indigestion, Gastric Hyperacidity, Peptic ulcer disease, Gastroesophageal reflux disorder (GERD)

Pharmacology

Aluminum hydroxide neutralizes stomach hydrocloride to form AICI3 salt plus water; increases gastric pH.

Magnesium Trisilicate neutralizes gastric acidity by increasing gastric pH

Dosage And Administration

Take 2-4 teaspoonful after meals and at bedtime as needed (up to 4 times a day)

Interaction

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.

Magnesium Trisilicate: None well documented.

Contraindications

Hypophosphataemia

Side Effects

Diarrhoea, constipation, nausea, vomiting.

Pregnancy And Lactation

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions And Warnings

Renal dysfunction, low phosphate diet, prolonged use.

Therapeutic Class

Antacid with laxative action, Antacids