Dolocid Oral Suspension
Indications
Aluminium Oxide & Magnesium Trisilicate is indicated in Heartburn, Indigestion, Gastric Hyperacidity, Peptic ulcer disease, Gastroesophageal reflux disorder (GERD)
Pharmacology
Aluminum hydroxide neutralizes stomach hydrocloride to form AICI3 salt plus water; increases gastric pH.
Magnesium Trisilicate neutralizes gastric acidity by increasing gastric pH
Dosage And Administration
Take 2-4 teaspoonful after meals and at bedtime as needed (up to 4 times a day)
Interaction
Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
Magnesium Trisilicate: None well documented.
Contraindications
Hypophosphataemia
Side Effects
Diarrhoea, constipation, nausea, vomiting.
Pregnancy And Lactation
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Precautions And Warnings
Renal dysfunction, low phosphate diet, prolonged use.
Therapeutic Class
Antacid with laxative action, Antacids