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Indications

Mebeverine is indicated for the:

  • Symptomatic treatment of irritable bowel syndrome (IBS)
  • Chronic irritable colon
  • Spastic constipation
  • Mucous colitis
  • Colicky abdominal pain
  • Persistent non-specific diarrhoea

Dosage And Administration

For adults, elderly and children over 10 years:

  • Mebeverine Hydrochloride 135 mg tablet: 1 tablet 03 times daily.
  • Mebeverine Hydrochloride 200 mg capsule: 1 capsule 02 times daily.

This is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.

Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.
 

Contraindications

Hypersensitivity to the drug or any other ingredients.

Side Effects

Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.

Pregnancy And Lactation

No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Mebeverine does not excrete in the breast milk after administering at therapeutic dose.

Precautions And Warnings

Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.

Overdose Effects

On theoretical grounds it may be predicted that CNS excitability will occur in case of overdosage. No specific antidote is known: gastric lavage and symptomatic treatment is recommended.

Therapeutic Class

Anticholinergics

Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children.