<p><strong>Pediatric Use</strong>: The safety and effectiveness of this oral solution in pediatric patients has not been established.<br />
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<strong>Renal Insufficiency</strong>: Patients with impaired renal function or patients taking concomitant medications that may affect renal function (such as diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers or patients of the importance of adequate hydration before, during and after the use of this oral solution. In patients with severely reduced renal function (creatinine clearance &lt;30 mL/min), accumulation of magnesium in plasma may occur.</p>