<p>Pregnancy Category C.&nbsp;There are no adequate and well-controlled studies in pregnant women with articaine with epinephrine. This&nbsp;should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.<br />
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Nursing Mothers: It is not known whether Articaine and Epinephrine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this combination&nbsp;is administered to a nursing woman.</p>