<p>Combination of Pioglitazone and Glimepiride is contraindicated in patients with:</p>

<ul>
	<li>Known hypersensitivity to Pioglitazone or Glimepiride or any of the components of combination of Pioglitazone or Glimepiride.</li>
	<li>Diabetic ketoacidosis, with or without coma. This condition should be treated with insulin.</li>
</ul>