<ul>
	<li>Hypersensitivity to Empagliflozin and Metformin</li>
	<li>Any type of acute metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis)</li>
	<li>Diabetic pre-coma</li>
	<li>Severe renal failure (GFR &lt;30 ml/min)</li>
	<li>Acute conditions with the potential to alter renal function such as: dehydration, severe infection, shock</li>
	<li>Disease which may cause tissue hypoxia (especially acute disease, or worsening of chronic disease) such as: decompensated heart failure, respiratory failure, recent myocardial infarction, shock</li>
	<li>Hepatic impairment, acute alcohol intoxication, alcoholism</li>
</ul>