<p>Pregnancy Category C. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher&nbsp;incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin monotherapy be used during pregnancy to maintain blood glucose levels as close to normal as possible. Combination of Rosiglitazone and Metformin should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. There are no adequate and well-controlled studies in pregnant women with combination of Rosiglitazone and Metformin or its individual components.<br />
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It is not known whether Rosiglitazone and/or Metformin are excreted in human milk. Because many drugs are excreted in human milk,&nbsp;a combination of Rosiglitazone and Metformin should not be administered to a nursing woman.</p>