<p>Citicoline is a naturally occurring substance that is an essential intermediate in the synthesis of structural phospholipids of cell membrane. Oral dose of Citicoline is metabolized to choline &amp; cytidine. These then enter into the systemic circulation, cross the blood-brain barrier and recombine to form Citicoline within the central nervous system. Citicoline activates the biosynthesis of structural phospholipids in the neuronal membrane, promotes rapid repair of injured cell surface &amp; mitochondrial membrane &amp; increases the level of various neurotransmitters like acetylcholine &amp; dopamine. Citicoline has neuroprotective effects in situations of hypoxia &amp; ischemia, as well as improved learning &amp; memory performance in animal models for the aging brain. Citicoline inhibits the activation of Phospholipase A2 to prevent apoptotic &amp; necrotic cell death.</p>