<p>Chlorthalidone is usually given at a dose of 25 mg daily; the usual initial dose of Atenolol is 50 mg daily. Therefore, the initial dose should be one Chlorthalidone 25 &amp; Atenolol 50 mg once a day. If an optimal response is not achieved, the dosage should be increased to one Chlorthalidone 25 &amp; Atenolol 100 mg&nbsp;once a day. Dose of two tablets once daily should not be used as initial therapy in elderly patients.</p>