<p>Based on information available to date for patients with impaired renal function, the initial dose can remain unchanged as can the interval between doses. However, the amount administered as the maintenance dose should be changed according to the following criteria:</p>

<ul>
	<li><strong>CrCl 30 ml/min or greater</strong>: full dosage</li>
	<li><strong>CrCl 10-30 ml/min</strong>: 50% dosage</li>
	<li><strong>CrCl &lt;10 ml/min</strong>: 25% dosage</li>
</ul>

<p>Use of Pivmecillinam in infants under 3 months of age should be avoided.</p>