<p><strong>Tablet</strong>: Adult:</p>

<ul>
	<li><strong>Respiratory Tract Infections</strong>: 500 to 750 mg twice daily (7 to 14 days)</li>
	<li><strong>Urinary tract infections</strong>: 250 to 750 mg twice daily (3 to 10 days)</li>
	<li><strong>Pelvic Inflammatory Diseases</strong>: 500 to 750 mg twice daily (14 days)</li>
	<li><strong>Infectious Diarrhea (Shigella dysenteriae, Vibrio cholera)</strong>: 500 mg twice daily (1 to 5 days)</li>
	<li>Typhoid fever: 500 mg twice daily (7 days)</li>
	<li><strong>Intra-abdominal infections</strong>: 500 to 750 mg twice daily (5 to 14 days)</li>
	<li><strong>Prostatitis</strong>: 500 to 750 mg twice daily (2 to 6 weeks)</li>
	<li><strong>Skin and Soft Tissue Infections</strong>: 500 to 750 mg twice daily (7 to 14 days)</li>
	<li><strong>Bone and Joint Infections</strong>: 500 to 750 mg twice daily (max. 3 months)</li>
	<li><strong>Gonorrhea</strong>: 500 mg as a single dose</li>
	<li><strong>Neutropenic patients with fever due to bacterial infection</strong>: 500 to 750 mg twice daily co-administered with appropriate antibacterials.</li>
	<li><strong>Meningitis</strong>: 500 mg as a single dose.</li>
	<li><strong>Surgical prophylaxis</strong>: 500 mg as a single dose, 60 minutes before the procedure.</li>
</ul>

<p><strong>Suspension</strong>: Pediatric: 10-20 mg/kg (max. 750 mg) twice daily (10 to 21 days). The duration of therapy depends on the type and severity of the infection.<br />
<br />
<strong>Extended-release tablet</strong>: In uncomplicated urinary tract infection (acute cystitis), the recommended dose of extended-release tablet is 1000 mg tablet once daily for three days.<br />
<br />
For IV infusion:</p>

<ul>
	<li><strong>Urinary Tract Infection</strong>: Mild to Moderate: 200 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 12 hourly for 7-14 days</li>
	<li><strong>Lower Respiratory Tract infection</strong>: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days</li>
	<li><strong>Nosocomial Pneumonia</strong>: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days</li>
	<li><strong>Skin and Skin Structure</strong>: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days</li>
	<li><strong>Bone and Joint Infection</strong>: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Complicated: 400 mg 8 hourly for more than 4-6weeks</li>
	<li><strong>Intraabdominal (Acute abdomen)</strong>: Complicated: 400 mg 12 hourly for 7-14 days</li>
	<li><strong>Acute Sinusitis</strong>: Mild/Moderate: 400 mg 12 hourly for 10 days</li>
	<li><strong>Chronic Bacterial Prostatitis</strong>: Mild/Moderate: 400 mg 12 hourly for 28 Days.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Instruction for the use of Ciprofloxacin IV infusion-</p>

<ul>
	<li>Check the bag for minute leaks by squeezing the inner bag firmly. If leaks are found, or if seal is not intact, discard the solution.</li>
	<li>Do not use if the solution is cloudy or a precipitate is present.</li>
	<li>Do not use flexible bags in series connections.</li>
	<li>Close flow control clamp of administration set.</li>
	<li>Remove cover from port at bottom of bag.</li>
	<li>Insert piercing pin of administration set into port with a twisting motion until the pin is firmly seated.</li>
	<li>Suspend bag from hanger.</li>
	<li>Squeeze and release drip chamber to establish proper fluid level in chamber during infusion of Ciprofloxacin IV infusion.</li>
	<li>Open flow control clamp to expel air from set.Close clamp.</li>
	<li>Regulate rate of administration with flow control clamp</li>
</ul>

<p><strong>Duration of treatment</strong>: The duration of treatment depends upon the severity of infection, clinical response and bacteriological findings. For acute infections the usual treatment period is 5 to 10 days. Generally treatment should be continued for 3 days after the signs and symptoms of the infection have been disappeared.</p>