<p>Drug Interactions-</p>

<ul>
	<li><strong>Potentially hazardous interactions</strong>: Little or no data are available in patients with markedly impaired cardiac left ventricular function; however, as with other calcium antagonist drugs, the combination of Amlodipine and p-blockers should be avoided in such patients.</li>
</ul>

<p>Other Significant Interactions-</p>

<ul>
	<li><strong>Digoxin</strong>: Absence of any interaction between Amlodipine and Digoxin in healthy volunteers has been documented in a controlled clinical study.</li>
	<li><strong>Cimetidine</strong>: An unpublished clinical study indicated no interaction between, Amlodipine and Cimetidine in healthy volunteers.</li>
	<li><strong>Warfarin</strong>: An unpublished clinical study in healthy volunteers indicates that Amlodipine did not significantly alter the effect of Warfarin on prothrombin time.</li>
	<li><strong>Food</strong>: Food does not alter the rate or extent of absorption of Amlodipine.</li>
</ul>