<p><strong>Use in children</strong>: Bupivacaine Hydrochloride is not recommended in patients younger than 18 years of age.<br />
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<strong>Use in elderly and renal impairment</strong>:&nbsp;Patients in poor general condition due to ageing or other compromising factors such as partial or complete heart conduction block, advanced liver or renal dysfunction require special attention, although regional anesthesia may be the optimal choice for surgery in these patients.</p>