<p>Sulphadoxine &amp; Pyrimethamine at the recommended dose is well tolerated. Main side effects are given below</p>

<ul>
	<li><strong>Skin reactions</strong>: Drug rash, pruritus and slight hair loss have been observed.</li>
	<li><strong>Gastro-intestinal reactions:</strong>&nbsp;Feeling of fullness, nausea, rarely vomiting, stomatitis.</li>
	<li><strong>Haematological reactions</strong>: In rare cases, leukopenia, thrombocytopenia, and megaloblastic anemia have been observed.</li>
	<li><strong>Other reactions</strong>: Fatigue, headache, fever, polyneuritis may occasionally occur.</li>
</ul>