<p>Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. Whether Trihexyphenidyl may best be given before or after meals should be determined by the way the patient reacts.<br />
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<strong>Idiopathic Parkinsonism</strong>: 1 mg of Trihexyphenidyl may be administered the first day. The dose may then be increased by 2mg increments at intervals of three to five days.<br />
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<strong>Drug-Induced Parkinsonism</strong>: Commence therapy with a single 1 mg dose increase the total daily dosage to 5-15 mg range if the extrapyramidal manifestations are not controlled.<br />
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<strong>Concomitant Use with Levodopa</strong>: When Trihexyphenidyl is used concomitantly with levodopa, the usual dose is 3-6 mg daily.</p>