<p><strong>Rifampicin:</strong>&nbsp;Induces microsomal enzymes (accelerates clearance of methadone, oral anticoagulants, glucocorticoids, oestrogen, oral hypoglycaemic agents, digitoxin, antiarrhythmics, theophylline, anticonvulsants, azole antifungal, cyclosporin).<br />
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<strong>Isoniazid:</strong>&nbsp;Inhibits metabolism of antiepileptics, benzodiazepines, warfarin, theophylline. Increases metabolism of enflurane. Alcohol, ASA, Al-containing antacids, corticosteroids, ketoconazole, propranolol.<br />
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<strong>Pyrazinamide:</strong>&nbsp;Decreases efficacy of gout therapy agents.<br />
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<strong>Ethambutol:</strong>&nbsp;Neurotoxic agents.</p>