<p><strong>Adult</strong>: 6 to 9 Million International Units per 24 hours, in 2 divided doses. In severe infections, the daily dosage may be increased to 12 to 15 Million International Units per day. Gonorrhea: 12 to 13.5&nbsp; Million International Units in a single dose.<br />
<br />
<strong>Children</strong>: The usual daily dosage is based on 150,000 l.U./kg body weight in 2 or 3 divided doses.</p>

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<p><strong>Administration</strong></p>

<p>Spiramycin is stable in gastric juices and absorption is not affected by food. In severe infections, the daily dosage may be increased by one half. In the treatment of beta hemolytic streptococcal infections, adequate Spiramycin dosage should be administered for 10 days.</p>