<p><strong>Pediatric Use</strong>: Safety and effectiveness of Paliperidone Palmitate in patients &lt;18 years of age have not been established.<br />
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<strong>Renal Impairment</strong>: Not recommended in patients with moderate or severe renal impairment<br />
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<strong>Hepatic Impairment</strong>: Paliperidone has not been studied in patients with hepatic impairment. Based on a study with oral paliperidone, no dose adjustment is required in patients with mild or moderate hepatic impairment.</p>