<p><strong>Elderly population</strong>: It can be used at the recommended dose in elderly patients.<br />
<strong>Renal impairment</strong>: No dosage adjustment is required in patients with renal impairment.<br />
<strong>Hepatic impairment</strong>: Caution should be observed in patients with moderate or severe hepatic impairment.<br />
<strong>Pediatric population</strong>: The safety and efficacy of this combination in children have not been established. No data are available.</p>