<p><strong>Hypertension</strong>: A patient whose blood pressure is not controlled with Valsartan and Hydrochlorothiazide monotherapy, should switch to Valsartan and Hydrochlorothiazide combination once daily. Highest allowed dose of Valsartan should not be greater than 320 mg in combination with hydrochlorothiazide 25 mg.&nbsp;<br />
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<strong>For Elderly</strong>: No initial dosage adjustment is necessary for elderly patients.<br />
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<strong>Pediatric use</strong>: Safety and effectiveness in pediatric patients have not been established.</p>