<p>Elagolix is contraindicated in women:</p>

<ul>
	<li>Who are pregnant</li>
	<li>Exposure to ORILISSA early in pregnancy may increase the risk of early pregnancy loss.</li>
	<li>With known osteoporosis because of the risk of further bone loss</li>
	<li>With severe hepatic impairment because of the risk of bone loss</li>
	<li>With concomitant use of strong organic anion transporting polypeptide (OATP) 1B1 inhibitors (e.g., cyclosporine and gemfibrozil)</li>
</ul>