<p><strong>Pediatric use</strong>: The recommended dose for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in patients 6 months to 17 years of age is based on extrapolation of efficacy from adults 18 years of age and older.<br />
<br />
<strong>Geriatric use</strong>: In clinical studies, each approved indication did not include sufficient numbers of patients aged 65 years and older to determine whether they respond differently than younger patients.<br />
<br />
<strong>Hepatic impairment</strong>: No dosage adjustment is required in patients with solely hepatic impairment.<br />
<br />
<strong>Renal impairment</strong>:</p>

<ul>
	<li>Mild renal impairment (creatinine clearance: 50-80 ml/min): a dose of 2.5 mg once daily is recommended.</li>
	<li>Moderate renal impairment (creatinine clearance: 30-50 ml/min): a dose of 2.5 mg once every other day is recommended.</li>
	<li>Severe renal impairment (creatinine clearance: 10-30 ml/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended.</li>
	<li>End-stage renal disease patients (creatinine clearance: &lt;10 ml/min) and patients undergoing hemodialysis: should not receive Levocetirizine.</li>
</ul>