<p>A thick layer of Lidocaine &amp; Prilocaine cream is applied to intact skin and covered with an occlusive dressing.<br />
<br />
<strong>Minor Dermal Procedures</strong>: For intravenous cannulation and venipuncture, apply 2.5 grams of&nbsp;Lidocaine &amp; Prilocaine cream over 20 &ndash; 25cm2 of skin surface for at least 1 hour.<br />
<br />
<strong>Major Dermal Procedures</strong>: For more painful dermatological procedures involving a larger skin&nbsp;area, apply 2grams of Lidocaine &amp; Prilocaine cream per 10cm2 of skin and allow to remain in contact with the&nbsp;skin for at least 2 hours.<br />
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<strong>Adult Male Genital Skin</strong>: As an adjunct prior to local anesthetic infiltration, apply a thick layer of&nbsp;Lidocaine &amp; Prilocaine cream to the skin surface for 15 minutes. Local anesthetic infiltration should be&nbsp;performed immediately after removal of Lidocaine &amp; Prilocaine cream.&nbsp;<br />
<br />
<strong>Adult Female Genital&nbsp;Mucous Membranes</strong>: For minor procedures on the female&nbsp;external genitalia, such as removal of condylomata acuminata, as well as for use as pretreatment&nbsp;for anesthetic infiltration, apply a thick layer (5-10 grams) of Lidocaine &amp; Prilocaine cream for 5 to 10 minutes.&nbsp;Occlusion is not necessary for absorption, but may be helpful to keep the cream in place.&nbsp;Patients should be lying down during the Lidocaine &amp; Prilocaine cream application, especially if no occlusion is&nbsp;used. The procedure or the local anesthetic infiltration should be performed immediately after&nbsp;the removal of Lidocaine &amp; Prilocaine cream.<br />
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<strong>Pediatric Patients</strong>: The following are the maximum recommended doses, application areas and&nbsp;application times for Lidocaine &amp; Prilocaine cream based on a child&rsquo;s age and weight:</p>

<ul>
	<li><strong>0 to 3 months or &lt;5 kg</strong>: Maximum Total Dose&nbsp;1 gm,&nbsp;Maximum Application Time: 1 hour</li>
	<li><strong>3 to 12 months and &gt;5 kg</strong>:&nbsp;Maximum Total Dose 2 gm, Maximum Application Time 4 hour</li>
	<li><strong>1 to 6 years and &gt;10 kg</strong>:&nbsp;Maximum Total Dose 10 gm, Maximum Application Time 4 hour</li>
	<li><strong>7 to 12 years and &gt;20 kg</strong>:&nbsp;Maximum Total Dose 20 gm, Maximum Application Time 4 hour</li>
</ul>