<p><strong>The usual recommended dose</strong>: Progesterone 100mg/200mg 2 to 3 soft gel capsules daily by the oral or vaginal routes in divided doses. Flexible dosage regimen can be followed depending on the indication and requirements of patients.<br />
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<strong>Maintenance of Pregnancy in cases of Threatened / Recurrent abortion</strong>: Progesterone 200 to 400 mg per day in divided doses.<br />
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<strong>In-vitro fertilization and embryo transfer</strong>: Progesterone 200 mg thrice a day from the day of embryo transfer till pregnancy is confirmed. If pregnant, it is continued till 12th&nbsp;week of pregnancy.<br />
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<strong>HRT</strong>: In sequential regimen: Progesterone 200mg daily for 12 days in last 2 weeks of each therapeutic cycle. In continuous regimen: Progesterone 100 mg daily throughout the month along with estrogen.<br />
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<strong>Oocyte donation program</strong>: Progesterone 100mg twice daily from the day of transfer till pregnancy is confirmed. This may be increased to a maximum of 600 mg per day and continued till 12th&nbsp;week of pregnancy.<br />
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<strong>Luteal support</strong>: Progesterone 100mg thrice a day from the 17th&nbsp;day of the cycle for 10 days in induced cycle. If pregnant, it is continued till 12th&nbsp;week of pregnancy.<br />
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<strong>Luteal phase insufficiency</strong>: Progesterone 10mg thrice daily to be continued up to 12 weeks of pregnancy, increasing the dose by 100mg/day/week to a maximum of 600mg/day in divided doses if required.<br />
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<strong>In secondary amenorrhoea</strong>: Progesterone 300mg for 10 days results in withdrawal bleeding in 80% of cases.<br />
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<strong>Premenstrual syndrome</strong>: Progesterone 100-200mg daily for 10 days from 17th&nbsp;to 26th&nbsp;day of each menstrual cycle.<br />
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<strong>Benign mastopathy</strong>: Progesterone 200-300 mg for 10 days per month, usually from 17th&nbsp;to 26th&nbsp;day of the monthly cycle.</p>