<p><strong>Effects of sitagliptin on other Drugs</strong>: Sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, warfarin, or oral contraceptive.<br />
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<strong>Digoxin</strong>: Sitagliptin slightly increases the mean of Digoxin concentration. However, no dose adjustment of either drug is required.</p>