<p><strong>Preparation</strong>:</p>

<ul>
	<li>Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. If either of these two conditions exists, the vaccine should not be administered.</li>
	<li>Do not mix Pneumococcal Vaccine with other vaccines in the same syringe or vial.</li>
	<li>Use a separate sterile syringe and needle for each individual patient to prevent transmission of infectious agents from one person to another.</li>
</ul>

<p><strong>Single-Dose Vial</strong>: Withdraw 0.5 mL from the vial using a sterile needle and syringe free of preservatives, antiseptics, and detergents.<br />
<br />
<strong>Single-Dose, Prefilled Syringe</strong>: The package does not contain a needle. Attach a sterile needle to the prefilled syringe by twisting in a clockwise direction until the needle fits securely on the syringe.<br />
<br />
<strong>Administration</strong>:<br />
<br />
Administer Pneumococcal Vaccine&nbsp;intramuscularly or subcutaneously into the deltoid muscle or lateral mid-thigh. Do not inject intravascularly or intradermally.<br />
<br />
<strong>Single-Dose Vial</strong>: Administer a single 0.5-mL dose of Pneumococcal Vaccine using a sterile needle and syringe. Discard vial after use.<br />
<br />
<strong>Single-Dose, Prefilled Syringe</strong>: Administer the entire contents of the single-dose, prefilled syringe per standard protocol using a sterile needle. Discard syringe after use.<br />
<br />
<strong>Revaccination</strong>: The Advisory Committee on Immunization Practices (ACIP) has recommendations for revaccination against pneumococcal disease for persons at high risk who were previously vaccinated with Pneumococcal Vaccine. Routine revaccination of immunocompetent persons previously vaccinated with a 23-<br />
valent vaccine, is not recommended.</p>