<p>Rivastigmine capsule-</p>

<ul>
	<li><strong>Initial dose</strong>: Rivastigmine 1.5 mg twice a day.</li>
	<li><strong>Dose titration:</strong>&nbsp;The starting dose is Rivastigmine 1.5 mg twice a&nbsp;day. If this dose is well tolerated after a minimum of two weeks of treatment, the dose&nbsp;may be increased to Rivastigmine 3 mg twice a day. Subsequent&nbsp;increases to 4.5 mg and then 6 mg twice a day should also be based on good tolerability&nbsp;of the current dose and may be considered after a minimum of two weeks of treatment at&nbsp;that dose level.</li>
	<li><strong>Maintenance dose</strong>: The effective dose is 3 mg to 6 mg twice a day; to achieve maximum therapeutic benefit patients should be maintained on their highest well tolerated dose. The recommended maximum&nbsp;daily dose is 6 mg twice a day. Maintenance treatment can be&nbsp;continued for as long as a therapeutic benefit for the patient exists.&nbsp;</li>
	<li><strong>Re-initiation of therapy</strong>: If treatment is interrupted for more than several days, it should be re-initiated at 1.5 mg twice daily. Dose titration should then be carried out as described above.</li>
</ul>

<p>Rivastigmine transdermal patch: Apply patch on intact skin for a 24-hour period; replace with a new patch every 24 hours.</p>

<ul>
	<li><strong>Initial Dose</strong>: Initiate treatment with 4.6 mg/24 hours Rivastigmine transdermal patch.</li>
	<li><strong>Dose Titration</strong>: After a minimum of 4 weeks, if tolerated, increase dose to 9.5 mg/24 hours, which is the minimum effective dose. Following a minimum additional 4 weeks, may increase dosage to maximum dosage of 13.3 mg/24 hours.</li>
	<li><strong>Mild to Moderate Alzheimer&#39;s Disease and Parkinson&rsquo;s Disease Dementia</strong>: Rivastigmine transdermal patch 9.5 mg/24 hours or 13.3 mg/24 hours once daily.</li>
	<li><strong>Severe Alzheimer&rsquo;s Disease</strong>: Rivastigmine transdermal patch 13.3 mg/24 hours once daily.</li>
	<li>For treatment interruption longer than 3 days, retitrate dosage starting at 4.6 mg per 24 hours.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Rivastigmine should be administered twice a day, with morning and&nbsp;evening meals.</p>