<p><strong>Pediatric use</strong>: The safety and effectiveness of lomefloxacin in pediatric patients and adolescents less than 18 years of age have not been established. Lomefloxacin causes arthropathy in juvenile animals of several species.&nbsp;<br />
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<strong>Geriatric use</strong>: Of the total number of subjects in clinical studies of lomefloxacin, 25% were &ge;65 years and 9% were &ge; 75 years. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.</p>