<p><strong>Adults</strong>-<br />
Major depressive disorder:</p>

<ul>
	<li>Starting Dose: 50 mg</li>
	<li>Therapeutic Range: 50-200 mg</li>
</ul>

<p>Obsessive-compulsive disorder:</p>

<ul>
	<li>Starting Dose: 50 mg</li>
	<li>Therapeutic Range: 50-200 mg</li>
</ul>

<p>Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:</p>

<ul>
	<li>Starting Dose: 25 mg</li>
	<li>Therapeutic Range: 50-200 mg</li>
</ul>

<p><strong>Pediatric Patients (ages 6-12 years old)</strong>-<br />
Obsessive-compulsive disorder:</p>

<ul>
	<li>Starting Dose: 25&nbsp;mg</li>
	<li>Therapeutic Range: 50-200 mg</li>
</ul>

<p>The recommended interval between dose changes is one week.<br />
<br />
<strong>Premenstrual dysphoric disorder (PMDD)</strong>: Starting dosage for PMDD is 50 mg/day. Sertraline may be administered either continuously (every day throughout the menstrual cycle) or intermittently (starting the daily dosage 14 days prior to the anticipated onset of menstruation and continuing through the onset of menses). Intermittent dosing would be repeated with each new cycle.</p>

<ul>
	<li><strong>Continuous</strong>: Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.</li>
	<li><strong>Intermittent</strong>: Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle (and subsequent cycles).</li>
</ul>