<p>Oral-</p>

<ul>
	<li><strong>Reduction of harmful effects of folic acid antagonists</strong>: The dose is usually one 5-15 mg tablet every 6 hours for 2 to 3 days.</li>
	<li><strong>Megaloblastic anemia</strong>: In the treatment of Megaloblastic anemia, the dose is one 5-15 mg tablet daily.</li>
</ul>

<p>Intravenous-</p>

<ul>
	<li><strong>Advanced Colorectal Cancer</strong>: Folinic Acid is administered at 200 mg/m2&nbsp;by slow intravenous injection followed by 5-fluorouracil at 370 mg/m2&nbsp;by intravenous injection. Or 20 mg/m&nbsp; 2 by slow intravenous injection followed by 5-fluorouracil at 425 mg/m2&nbsp;by intravenous injection. Treatment is repeated daily for 5 days. This 5 day treatment course may be repeated at 4 weeks interval, for 2 courses and then may repeated at 4-5 weekly intervals if the patient has recovered completely from the toxic effects of the prior treatment course.</li>
	<li><strong>Folinic acid rescue after high dose Methotrexate Therapy</strong>: Calcium Folinate starts 24 hours after the beginning of the methotrexate infusion at dose of 15mg (10 mg/m2&nbsp;) every 6 hours for 10 doses.</li>
</ul>

<p>Intramuscular-</p>

<ul>
	<li><strong>Folate deficient megaloboastic anaemia</strong>: Up to 1 mg/day. Or, as directed by the registered physician.</li>
</ul>