<p>Other NSAIDs or aspirin: Increase the side effects of ketorolac Tromethamine.<br />
Anti-coagulants: Enhance anti-coagulant effect.<br />
Beta Blocker: Reduce the anti-hypertensive effect .<br />
ACE Inhibitors: Increase the risk of renal impairment.<br />
Methotrexate: Enhance the toxicity of methotrexate.</p>