<p><strong>Primary active immunization</strong>: Poliomyelitis vaccine is indicated for active immunization of infants, children and adults for the prevention of poliomyelitis caused by poliovirus types 1, 2 and 3. It is recommended that all infants, unimmunized children and adolescents not previously immunized be vaccinated routinely against paralytic poliomyelitis.<br />
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<strong>Immune deficiency and altered immune status</strong>: Patients with immuno-deficiencies status are at a greater risk of developing paralysis when exposed to poliovirus. Oral polio vaccine is contraindicated in such a patient.<br />
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Altered immune states due to disease and compromised immune system due to treatment with corticosteroids should be immunized with IPV according to the dosage schedule. Patients with altered immune status may or may not develop protective immune response after administration of IPV.</p>