<p><strong>Pregnancy</strong>&nbsp;Category C. There are no adequate or well-controlled studies of Neostigmine in either laboratory animals or in&nbsp;pregnantwomen. It is not known whether Neostigmine can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Neostigmine should be given to a pregnant woman only if clearly needed.<br />
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<strong>Nonteratogenic Effects</strong>: Anticholinesterase drugs may cause uterine irritability and induce premature&nbsp;labor&nbsp;when given intravenously to pregnant women near term.<br />
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<strong>Nursing Mothers</strong>: It is not known whether Neostigmine is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions from Neostigmine in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.</p>