<p>Opioid dependence:</p>

<ul>
	<li><strong>Initially</strong>:&nbsp;25 mg; increase to 50 mg daily if no withdrawal signs occur.</li>
	<li><strong>Maintenance</strong>: 350 mg wkly given as 50 mg daily or divided in 3 doses (given on 3 days of the wk) for improved compliance.</li>
</ul>

<p>Adjunct in alcohol dependence: 50 mg daily.</p>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>May be taken with or without food.</p>