<p>The recommended dose of Milnacipran&nbsp;is 100 mg/day (50 mg twice daily). Based on efficacy and tolerability dosing may be titrated according to the following schedule:<br />
<br />
<strong>Day 1</strong>:&nbsp;12.5 mg once<br />
<strong>Days 2-3</strong>:&nbsp;25 mg/day (12.5 mg twice daily)<br />
<strong>Days 4-7</strong>:&nbsp;50 mg/day (25 mg twice daily)<br />
<strong>After Day 7</strong>:&nbsp;100 mg/day (50 mg twice daily)<br />
<br />
Based on individual patient response, the dose may be increased to 200 mg/day (100 mg twice daily). Doses above 200 mg/day have not been studied.</p>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Should be taken with food. Preferably taken during meals.</p>