<p><strong>Hepatic impairment (Moderate to severe)</strong>: 50 mg daily. Max: 100 mg once daily.<br />
<br />
<strong>Renal Impairment</strong>:</p>

<ul>
	<li><strong>CrCl &lt;30 or ESRD</strong>:&nbsp;25 mg daily or 50 mg every other day. Supplemental doses should not be given after dialysis.</li>
	<li><strong>CrCl (30-50)</strong>: Max 50 mg once daily.</li>
</ul>