<p>Intravenous (Adult):</p>

<p><strong>Cervical cancer</strong>:&nbsp;30 mg/m2&nbsp;days 1 and 8 of a 21-day treatment cycle.<br />
<br />
<strong>Breast cancer, Ovarian cancer</strong>:&nbsp;25 mg/m2&nbsp;dose every 7 days.<br />
<br />
<strong>Non-small cell lung cancer</strong>:&nbsp;</p>

<ul>
	<li><strong>As single agent</strong>: 30 mg/m2&nbsp;wkly as infusion over 20-30 minutes (after diluting in 125 ml normal saline or glucose 5%) or as slow bolus over 5-10 minutes (after diluting in 20-50 ml normal saline or glucose 5%). Delay subsequent doses if neutrophil count is &lt;2000 cells/mm3&nbsp;until recovery.</li>
	<li><strong>As combination therapy with cisplatin</strong>: 25-30 mg/m2&nbsp;every 7 days.</li>
</ul>

<p>&nbsp;</p>

<p>Oral&nbsp;(Adult):</p>

<p><strong>Non-small cell lung cancer</strong>:&nbsp;60 mg/m2once wkly for 3 wk, may increase subsequently to 80 mg/m2&nbsp;once wkly. If neutrophil count is &lt; 500 cells/mm3&nbsp;or between 500-1000 cells/mm3&nbsp;on 2 separate occasions, keep dose at 60 mg/m2&nbsp;for next 3 doses.</p>