<p><strong>Co-administration with other drugs:</strong>&nbsp;Tenofovir should not be administered concurrently with Emtricitabine &amp; Tenofovir combination or Adefovir Dipivoxil.<br />
<br />
<strong>Lactic Acidosis &amp; Severe Hepatomegaly with Steatosis:</strong>&nbsp;Though the risk of occurrence of lactic acidosis is low for Tenofovir, treatment should be suspended in any patient who develops lactic acidosis or hepatotoxicity.<br />
<br />
<strong>Exacerbation of hepatitis after discontinuation of treatment:</strong>&nbsp;Discontinuation of Tenofovir<br />
therapy may be associated with severe acute exacerbation of hepatitis.</p>