<p>The most commonly reported adverse drug reactions (ADRs) with Ethinylestradiol &amp; Drospirenone are breast pain, female genital tract bleeding and gastrointestinal and abdominal pains. They occur in &gt;6% of users. Bleeding irregularities usually subside during continued treatment. The frequency of bleeding decreases with the duration of treatment. Serious adverse reactions are arterial and venous thromboembolic events as well as breast cancer</p>