<p><strong>Hypertension</strong>: The usual dose of Valsartan is 80 to 160 mg once daily. The maximum dose is 320 mg daily. Maximum blood pressure reduction occurs within 4 weeks.&nbsp;<br />
<br />
<strong>Heart failure</strong>:&nbsp;The usual dose is 40 mg twice daily and may be increased to 80-160 mg twice daily.&nbsp;<br />
<br />
<strong>Post-Myocardial Infarction</strong>:&nbsp;The initial dose after myocardial infarction is 20 mg twice daily. The dose should be increased with a target of 160 mg daily if tolerated without side effects.</p>

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<p><strong>Administration</strong></p>

<p>Administration of Valsartan with food decreases the absorption of Valsartan by about 40%, so it should be taken on an empty stomach. No initial dosage adjustment is required for elderly patients with mild to moderate renal and hepatic insufficiency.</p>