<p><strong>Intra-articular:</strong><br />
Supplement in systemic therapy for treatment of susceptible infections-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;500 mg daily.</li>
	<li><strong>Child</strong>:&nbsp;&lt;10 yr&nbsp;Half of adult routine dosage.</li>
</ul>

<p><strong>Intraperitoneal:</strong><br />
Supplement in systemic therapy for treatment of susceptible infections-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;500 mg daily.</li>
	<li><strong>Child</strong>:&nbsp;&lt;10 yr&nbsp;Half of adult routine dosage.</li>
</ul>

<p><strong>Intrapleural:</strong><br />
Supplement in systemic therapy for treatment of susceptible infections-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;500 mg daily.</li>
	<li><strong>Child</strong>:&nbsp;&lt;10 yr&nbsp;Half of adult routine dosage</li>
</ul>

<p><strong>Intravenous:</strong><br />
Meningitis-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;2 gm 6 hrly.</li>
	<li><strong>Child</strong>:&nbsp;150 mg/kg daily in divided doses.</li>
</ul>

<p>Intrapartum prophylaxis against group B Streptoccocal infection in neonates-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;Initially, 2 gm via IV inj followed by 1 gm 4 hrly until delivery.</li>
</ul>

<p><strong>Oral:</strong><br />
Biliary tract infections, Bronchitis, Endocarditis, Gastroenteritis, Listeriosis, Otitis media, Perinatal streptococcal infections, Peritonitis-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;0.25-1 gm 6 hrly.</li>
	<li><strong>Child</strong>:&nbsp;&lt;10 yr&nbsp;Half of adult routine dosage.</li>
</ul>

<p>Typhoid and paratyphoid fever-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;1-2 gm 6 hrly for 2 wk in acute infections, and 4-12 wk in carriers.</li>
</ul>

<p>Uncomplicated gonorrhoea-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;2 gm with 1 gm of probenecid as single dose, recommended to be repeated in female patients.</li>
</ul>

<p>Urinary tract infections-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;500 mg 8 hrly.</li>
</ul>

<p><strong>Parenteral:</strong><br />
Susceptible infections-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;500 mg 6 hrly, via IM or slow IV inj over 3-5 min or by infusion.</li>
	<li><strong>Child</strong>:&nbsp;&lt;10 yr&nbsp;Half of adult routine dosage.</li>
</ul>

<p>Septicaemia-</p>

<ul>
	<li><strong>Adult</strong>:&nbsp;150-200 mg/kg daily. Initiate with IV admin for at least 3 days, then continue with IM inj 3-4 hrly. Continue treatment for at least 48-72 hr after the patient has become asymptomatic or when there is evidence of bacterial eradication. Recommended treatment duration for infections caused by group-A &beta;-haemolytic streptococci: At least 10-days, to prevent occurrence of acute rheumatic fever or acute glomerulonephritis.</li>
	<li><strong>Child</strong>:&nbsp;Same as adult dose.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Should be taken on an empty stomach. Take 1 hr before or 2 hr after meals.</p>