<p>Oral:</p>

<ul>
	<li><strong>Benign gastric ulcer</strong>: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed.</li>
	<li><strong>Gastro-esophageal reflux disease</strong>: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily.</li>
	<li><strong>Duodenal ulcer</strong>: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed.</li>
	<li><strong>Duodenal ulcer associated with Helicobacter pylori</strong>: Pantoprazole is recommended at a dose of 40 mg twice daily in association with antimicrobial agents as detailed below: Amoxycillin 1 g and Clarithromycin 500 mg both twice daily for one week, or Clarithromycin 250 mg and Metronidazole 400 mg both twice daily for one week.</li>
	<li><strong>Prophylaxis of NSAID-associated gastric or duodenal ulcer</strong>: 20 mg daily for those require long-term NSAID treatment.</li>
	<li><strong>Zollinger-Ellison Syndrome</strong>: Initially 80 mg once daily adjusted according to response (elderly max. 40 mg daily); daily doses above 80 mg given in 2 divided doses.</li>
</ul>

<p><br />
IV Injection:</p>

<ul>
	<li><strong>Duodenal ulcer and gastric ulcer</strong>:&nbsp;40 mg once daily for 7-10 days</li>
	<li><strong>Gastroesophageal reflux disease associated&nbsp;with a history of erosive esophagitis</strong>:&nbsp;40 mg once daily for 7-10 days</li>
	<li><strong>Prevention of rebleeding in peptic ulcer</strong>:&nbsp;IV 80 mg, followed by 8 mg/hour infusion for 72 hours</li>
	<li><strong>Prophylaxis of acid aspiration</strong>: 80 mg IV every 12 h for 24 h, followed by 40mg every 12 hour</li>
	<li><strong>Long-term management of Zollinger-Ellison Syndrome and other pathological hypersecretory conditions</strong>: 80 mg IV every 12 hours, may increase to 80 mg every 8 hours&nbsp;if needed, may titrate to higher doses depending on acid output.</li>
</ul>