<p><strong>Pregnancy</strong>: There are no adequate and well-controlled studies of Netarsudil ophthalmic solution in pregnant women to inform any drug-associated risk. However, systemic exposure to Netarsudil from ocular administration is low.<br />
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<strong>Lactation</strong>: There are no data on the presence of Netarsudil in human milk, the effects on the breastfed infant, or the effects on milk production.<br />
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<strong>Pediatric Use</strong>: Safety and effectiveness in pediatric patients below the age of 18 years have not been established.<br />
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<strong>Use in elderly patients</strong>: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.</p>