<p>Chemotherapy-Induced Nausea and Vomiting-<br />
Adults, Pediatric patients (6 months to 18 years):</p>

<ul>
	<li><strong>8 mg tablet/orodispersible tablet</strong>: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.</li>
	<li><strong>4 mg orodispersible tablet</strong>: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.</li>
	<li><strong>Injection</strong>: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes.</li>
</ul>

<p>Radiotherapy-Induced Nausea and Vomiting-<br />
Adults:</p>

<ul>
	<li><strong>8 mg tablet/orodispersible tablet</strong>: Initial Dose: 8 mg orally 1 to 2 hours before radiotherapy. Post Radiotherapy: 8 mg orally every 8 hours for up to 5 days after a course of treatment.</li>
	<li><strong>4 mg orodispersible tablet</strong>: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.</li>
	<li><strong>Injection</strong>: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes.</li>
</ul>

<p>Postoperative Nausea and Vomiting-<br />
Adults:</p>

<ul>
	<li><strong>8 mg tablet/orodispersible tablet</strong>: 16 mg given as two 8 mg tablets</li>
	<li><strong>4 mg orodispersible tablet</strong>: 16 mg</li>
	<li><strong>Injection</strong>: 4 mg</li>
</ul>

<p>Pediatrics (&gt;40 kg): Injection: 4 mg<br />
Pediatrics (40 kg): Injection: 0.1 mg/kg<br />
<br />
<strong>Oral Soluble Film:</strong><br />
Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy:</p>

<ul>
	<li><strong>Adult oral dose</strong>: 24 mg given successively as three 8 mg films 30 minutes before the start of chemotherapy.</li>
</ul>

<p>Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy:</p>

<ul>
	<li><strong>Adults and pediatric patients 12 years of age and older</strong>: One 8 mg film 30 minutes before chemotherapy followed by an 8 mg dose 8 hours later. Administer one 8 mg film twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy.</li>
	<li><strong>Pediatric patients 4 through 11 years of age</strong>: One 4 mg film three times a day. Administer the first dose 30 minutes before chemotherapy, with subsequent doses 4 and 8 hours later. Administer one 4 mg film three times a day (every 8 hours) for 1 to 2 days after completion of chemotherapy.</li>
	<li><strong>Prevention of nausea and vomiting associated with radiotherapy</strong>: The adult dosage is one 8 mg film three times a day.</li>
	<li><strong>Postoperative nausea and vomiting</strong>: The adult dose is 16 mg given successively as two 8 mg films 1 hour before anesthesia.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Administration of Oral Soluble Film:</p>

<ul>
	<li>Step 1:&nbsp;Tear the pouch carefully along with the edge tear mark.</li>
	<li>Step 2:&nbsp;Put the Ondansetron&nbsp;film on top of your tongue. It will dissolve within 20 seconds</li>
	<li>Step 3:&nbsp;Do not chew or swallow the film whole.</li>
	<li>Step 4:&nbsp;Swallow after the Onsaf oral soluble film dissolves. You may swallow the dissolved film with or without liquid.</li>
	<li>Step 5:&nbsp;Wash your hands after taking Onsaf oral soluble film</li>
</ul>