<p>The following adverse reactions have been reported in women taking Medroxyprogesterone Acetate tablets, without concomitant estrogens treatment:</p>

<ul>
	<li><strong>Genitourinary system</strong>: Abnormal uterine bleeding (irregular, increase, decrease), change in menstrual flow, breakthrough bleeding, spotting, amenorrhea, changes in cervical erosion and cervical secretions.</li>
	<li><strong>Breasts</strong>: Breast tenderness, mastodynia or galactorrhea has been reported.</li>
	<li><strong>Cardiovascular</strong>: Thromboembolic disorders including thrombophlebitis and pulmonary embolism have been reported.</li>
	<li><strong>Gastrointestinal</strong>: Nausea, cholestatic jaundice.</li>
	<li><strong>Skin</strong>: Sensitivity reactions consisting of urticaria, pruritus, edema and generalized rash have occurred. Acne, alopecia and hirsutism have been reported.</li>
	<li><strong>Eyes</strong>: Neuro-ocular lesions, for example, retinal thrombosis, and optic neuritis.</li>
	<li><strong>Central nervous system</strong>: Mental depression, insomnia, somnolence, dizziness, headache, nervousness.</li>
</ul>