<p><strong>Pediatric Use</strong>: Pediatric dose recommendations that are both reliably effective and below thresholds of concern with respect to QT and PR prolongation could not be determined<br />
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<strong>Geriatric Use</strong>: Caution should be exercised due to greater frequency of decreased hepatic, renal or cardiac function in elderly population.<br />
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<strong>Impaired Renal Function</strong>: No initial dose adjustment is necessary for patients with renal impairment.<br />
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<strong>Impaired Hepatic Function</strong>: No dose adjustment is necessary for patients with mild or moderate hepatic impairment.</p>