<p>Patients should not use Avanafil if sexual activity is inadvisable due to cardiovascular status or any other reason&nbsp;<br />
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Use of Avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension<br />
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Patients should seek emergency treatment if an erection lasts greater than 4 hours<br />
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Patients should stop Avanafil and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of Non Arteritic Ischemic Optic Neuropathy (NAION). Discuss with patients the increased risk of NAION in patients with a history of NAION<br />
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Patients should stop taking Avanafil and seek prompt medical attention in the event of sudden decrease or loss of hearing</p>