<p><strong>Adrenal insufficiency</strong>: 50 mg/day for 3 months is considered a replacement dose, while 200 mg/day achieves supraphysiological circulating levels and is considered a pharmacological dose.<br />
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<strong>Anorexia nervosa</strong>: 100 mg/day for 6 months was used in a pilot study.<br />
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<strong>Diminished ovarian reserve</strong>: 50 to 75 mg/day (in divided doses) has been used in clinical studies of assisted reproduction.<br />
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<strong>Exercise training&ndash;induced muscle damage</strong>: 100 mg/day of Dehydroepiandrosterone supplementation was administered over 5 days in a study in young men undergoing exercise training.<br />
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<strong>Major depressive disorder</strong>: Doses ranging from 30 to 450 mg/day for 6 to 8 weeks have been used in clinical studies.<br />
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<strong>Metabolic syndrome</strong>: 100 mg/day for 3 months has been used in a study evaluating effects against metabolic syndrome in pre-and postmenopausal women.<br />
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<strong>Postmenopausal women</strong>: 25 mg/day has been suggested because this dose minimizes androgenic adverse effects; however, only studies in which at least 50 mg/day was used demonstrated positive outcomes as hormonal replacement therapy.</p>