<p><strong>Paediatric use</strong>: Safety and effectiveness of Diclofenac Sodium and Misoprostol combination in paediatric patients have not been established.<br />
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<strong>Geriatric use</strong>: No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some elderly person cannot be ruled out. As with any NSAID, the elderly are likely to tolerate adverse events less well than younger patients.</p>