<p>Deferasirox is an orally active chelator that is selective for iron (as Fe3+ ). It is a tridentate ligand that binds iron with high&nbsp;affinity&nbsp;in a 2:1 ratio. Although deferasirox has very low affinity for zinc&nbsp;and copper there are variable decreases in the serum concentration of these trace metals after the administration of deferasirox. The clinical significance of these decreases is uncertain.</p>

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