<p>The recommended dose of Disopyramide is 400 mg /day in 4 divided doses (100 mg capsule 6 hourly).<br />
<br />
Patients with renal insufficiency should take 100 mg capsule according to the schedule given below:<br />
<br />
Creatinine clearance (ml/min) &gt;15: Approximate dosing q 8 hrq 12 hrq 24 hr<br />
<br />
Patients in whom rapid control of ventricular arrhythmia is essential, an initial loading dose of 300 mg Disopyramide is recommended, followed by the appropriate maintenance dosage.</p>