<p><strong>Dual Blockade of the Renin-Angiotensin-Aldosterone System</strong>: Should not be used with an ACEi, aliskiren in patients with diabetes, and use with an ARB should be avoided.<br />
<strong>Potassium-sparing Diuretics</strong>: Serum potassium level may be increased.<br />
<strong>NSAIDs</strong>: Risk of renal impairment may be increased.<br />
<strong>Lithium</strong>: Increased risk of lithium toxicity.</p>