<p><strong>Usual dose range</strong>: Upto 40 gm daily at a rate not exceeding 3 ml per minute<br />
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<strong>Seizure prophylaxis in Preeclampsia and Eclampsia</strong>: A loading dose of 4 gm (100 ml) over upto 20 minutes followed by a maintenance dose of 2 gm (50 ml) per hour. Recurrence of seizure may require an additional I.V bolus of 8-16 mmol (upto 100 ml). For seizure prophylaxis, treatment should continue during labour and for atleast 24 hours after delivery.<br />
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<strong>In Myocardial infarction</strong>: 8 mmol (50 ml) over 20 minutes, then 65 mmol (400 ml) over 24 hours.<br />
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<strong>In Magnesium deficiency</strong>: 0.5-1 mmol/kg/day (200 ml to 400 ml) on the first day followed by 25 mmol (150 ml) daily, upto 160 mmol (1000 ml) over upto 5 days.<br />
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<strong>In Tetanus</strong>: An infusion of Magnesium Sulphate sufficient to maintain a blood magnesium concentration of 2.5 to 4 mmol per litre has been recommended.<br />
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<strong>In arrythmia</strong>: 8 mmol (50 ml) over 10-15 minutes (repeated once if needed)</p>