<ul>
	<li><strong>Anticoagulants</strong>: Anticoagulant response (INR or prothrombin time) should be monitored frequently in order to adjust the anticoagulant dose as needed.</li>
	<li><strong>Phenytoin</strong>: Phenytoin levels should be monitored in patients taking Capecitabine concomitantly with phenytoin. The phenytoin dose may need to be reduced.</li>
	<li><strong>Leucovorin</strong>: The concentration of 5-fluorouracil is increased and its toxicity may be enhanced by leucovorin.</li>
	<li><strong>CYP2C9 substrates</strong>: Care should be exercised when Capecitabine is co-administered with CYP2C9 substrates.</li>
	<li><strong>Food</strong>: Reduced both the rate and extent of absorption of Capecitabine.</li>
</ul>