<p><strong>Adults and Pediatric Patients Over 12 Years</strong>: One 100 mg capsule every 12 hours for seven days. Capsules should be taken with food.<br />
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The administration of high doses of nitrofurantoin to rats causes temporary spermatogenic arrest; this is reversible on discontinuing the drug. Doses of 10 mg/kg/day or greater in healthy human males may, in certain unpredictable instances, produce a slight to moderate spermatogenic arrest with a decrease in sperm count.</p>