<p>Careful Administration (should be administered with care in following patients):</p>

<ul>
	<li>Patients who are receiving other antidiabetic drugs as hypoglycaemia may occur</li>
	<li>Patients with a history of laparotomy or ileus (intestinal obstruction-like symptoms are liable to develop due to an increase in intestinal gas, etc.)</li>
	<li>Patients with chronic intestinal disease accompanied by a disturbance in digestion and absorption (the action of this drug may aggravate the pathologic conditions)</li>
	<li>Patients with Roemheld&rsquo;s Syndrome, severe hernia, Stenosis or ulceration of the large intestine, etc. (Symptoms may worsen due to an increase in the intestinal gas, etc.)</li>
	<li>Patients with serious hepatic dysfunction (Because of possible changes in metabolic condition, the status of plasma glucose control may greatly vary. In patients with severe liver cirrhosis, hyperammonemia may worsen, followed by disturbance of consciousness.)</li>
	<li>Patients with serious renal dysfunction (Because of possible changes in metabolic conditions, the status of plasma glucose control may greatly vary.)</li>
	<li>Elderly patients</li>
</ul>