<p>Naloxone is indicated for the complete or partial reversal of opioid depression, including&nbsp;respiratory&nbsp;depression, induced by natural and synthetic opioids, including propoxyphene,&nbsp;methadone&nbsp;and certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine, butorphanol, and cyclazocine. Naloxone is also indicated for diagnosis of suspected or known&nbsp;acute&nbsp;opioid overdosage. Naloxone may be useful as an adjunctive agent to increase&nbsp;blood pressure in the management of&nbsp;septic&nbsp;shock.</p>