<p>The following diseases are reported more often in women using HRT compared to women not using HRT:</p>

<ul>
	<li>breast cancer</li>
	<li>abnormal growth or cancer of the lining of the womb (endometrial hyperplasia or cancer)</li>
	<li>ovarian cancer</li>
	<li>blood clots in the veins of the legs or lungs (venous thromboembolism)</li>
	<li>heart disease</li>
	<li>stroke</li>
	<li>probable memory loss if HRT is started over the age of 65 Other side effects that have been linked to the use of Estradiol Valerate and other oral hormone replacement therapies</li>
	<li>During the first few months of treatment you may experience some vaginal bleeding at unexpected times (breakthrough bleeding and spotting). These symptoms normally lessen with continued treatment. If they don&rsquo;t, contact your doctor (see section 2 HRT and cancer/Excessive thickening of the lining of the womb (endometrial hyperplasia) and cancer of the lining of the womb (endometrial cancer)&rsquo; for more information)</li>
	<li>breast pain, tenderness or enlargement, breast discharge</li>
	<li>painful periods, changes in vaginal secretions, pre-menstrual symptoms, increased size of fibroids in the womb, thrush, changes to the neck of the womb</li>
	<li>indigestion, a feeling of being bloated, passing wind, feeling or being sick, abdominal pain, gall bladder disease</li>
	<li>skin rashes or discolouration, itching, eczema, acne, unusual hair loss or hair growth, increased skin pigment especially on the face (chloasma other conditions for more information), some rare skin problems</li>
	<li>headache, migraine, dizziness, anxiety or depressive symptoms, fatigue</li>
	<li>fast or irregular heartbeat (palpitations), high blood pressure, inflammation of veins usually in the legs</li>
	<li>fluid retention leading to swelling of parts of the body</li>
	<li>changes in body weight and sex drive, increased appetite</li>
	<li>muscle cramps, leg pains</li>
	<li>nose bleeds, visual disturbances (such as blurred vision), discomfort with contact lenses, allergic-type reactions, a worsening of glucose tolerance, bladder inflammation, rare disorders (porphyria, chorea).</li>
</ul>