<p><strong>Rheumatoid Arthritis</strong>: Tofacitinib 5 mg twice daily or Tofacitinib 11 mg once daily.&nbsp;Recommended dosage in patients with moderate and severe renal impairment or moderate hepatic impairment is Tofacitinib 5 mg once daily.<br />
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<strong>Psoriatic Arthritis&nbsp;</strong>(in combination with nonbiologic DMARDs): Tofacitinib 5 mg twice daily or Tofacitinib 11 mg once daily.&nbsp; Recommended dosage in patients with moderate and severe renal impairment or moderate hepatic impairment is Tofacitinib 5 mg once daily.<br />
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<strong>Ulcerative Colitis</strong>: Tofacitinib 10 mg twice daily for at least 8 weeks; then 5 or 10 mg twice daily. Discontinue after 16 weeks of 10 mg twice daily, if adequate therapeutic benefit is not achieved. Use the lowest effective dose to maintain response.</p>