<p>This injection is contraindicated in patients with:</p>

<ul>
	<li>hypersensitivity to the active substances or to any of the excipients</li>
	<li>tumours of the hypothalamus and pituitary gland</li>
	<li>ovarian enlargement or ovarian cyst unrelated to polycystic ovarian disease and of unknown origin</li>
	<li>gynaecological haemorrhages of unknown origin</li>
	<li>ovarian, uterine or mammary carcinoma</li>
</ul>

<p>This injection must not be used when an effective response cannot be obtained, such as:</p>

<ul>
	<li>primary ovarian failure</li>
	<li>malformations of sexual organs incompatible with pregnancy</li>
	<li>fibroid tumours of the uterus incompatible with pregnancy</li>
</ul>