<ul>
	<li>Promethazine is contraindicated for use in children less than two years of age</li>
	<li>Hypersensitivity to promethazine or to any of the excipients.</li>
	<li>Phenergan should not be used in patients who are in a coma or suffering from CNS depression of any cause. It must not be given to neonates or premature infants.</li>
	<li>Phenergan should be avoided in patients who have been taking monoamine oxidase inhibitors within the previous 14 days</li>
</ul>