<p>Sotalol should not be given to patients with sinus, bradycardia, sick sinus&nbsp;syndrome or second or third degree AV block (unless a functional pacemaker is present);&nbsp;congenital or acquired long QT syndromes, torsades de pointes, uncontrolled congestive heart&nbsp;failure, cardiogenic shock; anaesthesia that produces myocardial depression, hypotension&nbsp;(except due to arrhythmia), severe peripheral circulatory disturbances, chronic obstructive airway&nbsp;disease or bronchial asthma, renal failure (ceratinine clearance &lt;40mL/min) and previous&nbsp;evidence of hypersensitivity to Sotalol. Sotalol should not be given to patients suffering from&nbsp;diabetic keto-acidosis or metabolic acidosis, therapy with Sotalol can be recommenced or&nbsp;resumed when the metabolic condition has been corrected.</p>