<p>Pregnancy Category A. A number of epidemiological studies suggest that there could possibly be an increased risk of oral clefts among newborns of women who were treated with systemic glucocorticosteroids during the first trimester of pregnancy. As a general rule, topical preparations containing corticoids should not be applied during the first trimester of pregnancy.<br />
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Lactation:&nbsp;The excretion of effective amounts of glucocorticoid with the breast milk is improbable.</p>