<p>The recommended dosage of alogliptin is 25 mg once daily with or without food.<br />
<br />
Patients with Renal Impairment:</p>

<ul>
	<li>No dose adjustment of Alogliptin is necessary for patients with mild renal impairment (creatinine clearance &ge;60 mL/min).</li>
	<li>The dose of Alogliptin is 12.5 mg once daily for patients with moderate renal impairment (creatinine clearance &ge;30 to &lt;60 mL/min).</li>
	<li>The dose of Alogliptin is 6.25 mg once daily for patients with severe renal impairment (creatinine clearance &ge;15 to &lt;30 mL/min) or with end-stage renal disease (ESRD) (creatinine clearance &lt;15 mL/min or requiring hemodialysis).</li>
</ul>

<p>Patients requiring hemodialysis can receive their dose of alogliptin without regard to the timing of the dialysis.</p>