<ul>
	<li>Coadministration with amiodarone may result in serious symptomatic bradycardia. Use of Ledipasvir and Sofosbuvir combination with Amiodarone is not recommended</li>
	<li>P-gp inducers (e.g., Rifampin, St. John&rsquo;s wort): May alter concentrations of Ledipasvir and Sofosbuvir. Use of Ledipasvir and Sofosbuvir combination with P-gp inducers is not recommended</li>
</ul>