<ul>
	<li>Concomitant use of Isosorbide Mononitrate with phosphodiesterase inhibitors in any form is contraindicated.</li>
	<li>Concomitant use of Isosorbide Mononitrate with riociguat, a soluble guanylate cyclase stimulator, is contraindicated.</li>
	<li>The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. Alcohol, in particular, has been found to exhibit additive effects of this variety.</li>
	<li>Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. Dose adjustments of either class of agents may be necessary.</li>
</ul>