<p>The following adverse events have been reported during therapy for HIV disease with Lamivudine.<br />
<br />
Blood and lymphatic systems disorders-</p>

<ul>
	<li><strong>Uncommon</strong>: Neutropenia, anaemia and thrombocytopenia</li>
	<li><strong>Very rare</strong>: Pure red cell aplasia</li>
</ul>

<p>Nervous system disorders-</p>

<ul>
	<li><strong>Common</strong>: Headache, insomnia</li>
	<li><strong>Very rare</strong>: Cases of peripheral neuropathy (or paraesthesia).</li>
</ul>

<p>Respiratory, thoracic and mediastinal disorders</p>

<ul>
	<li><strong>Common</strong>: Cough, nasal symptoms-</li>
</ul>

<p>Gastrointestinal disorders-</p>

<ul>
	<li><strong>Common</strong>: Nausea, vomiting, abdominal pain or cramps, diarrhea</li>
	<li><strong>Rare</strong>: Rises in serum amylase. Cases of pancreatitis have been reported.</li>
</ul>

<p>Hepatobiliary disorders-</p>

<ul>
	<li><strong>Uncommon</strong>: Transient rises in liver enzymes (AST, ALT).</li>
	<li><strong>Rare</strong>: Hepatitis</li>
</ul>

<p>Skin and subcutaneous tissue disorders-</p>

<ul>
	<li><strong>Common</strong>: Rash, alopecia</li>
</ul>

<p>Musculoskeletal and connective tissue disorders-</p>

<ul>
	<li><strong>Common</strong>: Arthralgia, muscle disorders</li>
	<li><strong>Rare</strong>: Rhabdomyolysis, Lipodystrophy</li>
</ul>

<p>General disorders and administration site conditions-</p>

<ul>
	<li><strong>Common</strong>: Fatigue, malaise, fever.</li>
</ul>

<p>Cases of lactic acidosis, usually associated with severe hepatomegaly and hepatic steatosis, have been reported with the use of nucleoside analogues.</p>