<p><strong>Dosage in renal impairment:</strong>&nbsp;In patients with a creatinine clearance between 60 and 30 ml/min, treatment should be initiated with Ramipril 1.25 mg monotherapy. If blood pressure is not adequately controlled, the dose of Ramipril may be increased to 2.5 mg. If blood pressure is still not controlled, patient may be switched to one tablet of Ramoril 2.5 Plus once daily. Dosage may be titrated upward to Ramoril 5 Plus until blood pressure is controlled.<br />
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<strong>Uue in children</strong>: Safety and effectiveness in paediatric patients have not been established.</p>