<p>Primary immunization for persons 7 years of age and older-</p>

<p>A series of three doses of 0.5 ml each, of adsorbed tetanus vaccine should be given intramuscularly</p>

<ul>
	<li><strong>First dose</strong>: At appropriate date</li>
	<li><strong>Second dose</strong>: 4 to 8 weeks after the first dose</li>
	<li><strong>Third dose</strong>: 6 to 12 months after the second dose</li>
</ul>

<p>Children older than 7 years who did not complete primary immunization series (e.g., previously received only two doses of DTaP or DTP) need to receive only one dose of tetanus toxoid adsorbed vaccine to complete the primary series of tetanus. Interruption of the recommended schedule with a delay between doses does not interfere with the final immunity achieved with adsorbed tetanus vaccine. There is no need to start the series over again, regardless of the time elapsed between doses.<br />
<br />
<strong>Routine booster injections</strong>: To maintain adequate protection, a booster dose of 0.5 ml of adsorbed tetanus vaccine every 10 years thereafter is recommended.<br />
&nbsp;</p>

<p>Vaccination of injured persons-</p>

<p>Clean and minor wound:</p>

<ul>
	<li>If primary immunization confirmed and receiving booster dose within previous 5 years, no need of additional vaccine.</li>
	<li>If primary immunization confirmed and receiving booster dose more than previous 5 years, 1 dose of 0.5 ml required.</li>
</ul>

<p>All other dirty wounds (contaminated with feces, soil, and saliva):</p>

<ul>
	<li>If primary immunization confirmed and receiving booster dose within previous 5 years, 1 dose of 0.5 ml required.</li>
	<li>If primary immunization confirmed and receiving booster dose more than previous 5 years, 1 dose of 0.5 ml along with tetanus immunoglobulin required.</li>
</ul>

<p>If a person has no previous vaccination or uncertain, the primary series of 3 doses of 0.5ml adsorbed tetanus vaccine should be given along with tetanus immunoglobulin with 1st dose.<br />
&nbsp;</p>

<p>Protection of neonatal tetanus-</p>

<p>For prevention of neonatal tetanus, adsorbed tetanus vaccine is recommended for immunization of women of childbearing age.<br />
<br />
<strong>Women (15-49 Years)</strong>: For pregnant woman who have not had previous immunization, 2 doses of tetanus toxoid at four weeks interval preferably during the last two trimester or at least 2 weeks before delivery should be given during pregnancy so that protective antibody would be transferred to the infant in order to prevent neonatal tetanus, e.g. 1 dose of 0.5 ml at 6th month of pregnancy and 1 dose of 0.5 ml at 7th month of pregnancy. Pregnant woman who have completed the course of tetanus, next 10 years no need of additional dose during pregnancy. Thereafter a single booster dose would be sufficient to extend immunity.</p>

<p><strong>Method of administration</strong>: Adsorbed Tetanus Vaccine is for intramuscular injection only. Do not inject intravenously. For adults and older children Adsorbed Tetanus Vaccine should be given intramuscularly in the deltoid muscle. For infants Adsorbed Tetanus Vaccine should be given intramuscularly in the anterolateral aspect of the upper thigh. It should not be injected into the gluteal areas as the immune response may be lower. The attending physician should determine final selection of the injection site and needle size, depending upon the patient&#39;s age and the size of the target muscle. The vaccine should be shaken well before use to obtain a homogenous turbid white suspension. Please do not shake vigorously.<br />
<br />
<strong>Preparation for administration:</strong></p>

<ul>
	<li>The vaccine should be shaken well before use to obtain a homogenous turbid white suspension. Please do not shake vigorously.</li>
	<li>The vaccine should be inspected visually for particulate matter and discoloration prior to administration. If either of these conditions exist, the vaccine should not be administered.</li>
	<li>The vaccine should be used as supplied; no dilution is necessary.</li>
	<li>The full recommended dose of the vaccine should be used. Any vaccine remaining in a single-dose ampoule/vial should be discarded.</li>
</ul>

<p><strong>Co-administration</strong>: Adsorbed tetanus vaccine can be given at the same time with other vaccine as diphtheria, tetanus, pertussis (DTP), polio (OPV), measles, mumps and rubella (MMR), Haemophilus Influenzae type b (Hib) and Meningococcal vaccines at separate sites with separate syringes. It should not be mixed with other vaccines or medicinal products in the same syringe.</p>