<ul>
	<li>Other NSAIDs, including high doses of salicylates: Administration of several NSAIDs together may increase the risk of ulcers and of gastrointestinal bleeding, via a synergistic effect.</li>
	<li>Oral anticoagulants, heparin and ticlopidine: Increased risk of bleeding via inhibition of platelet function and damage to the gastroduodenal mucosa. Careful monitoring of the effects of anticoagulants is thus essential if it proves impossible to avoid such combined prescription.</li>
	<li>Lithium: NSAIDs increase blood lithium levels, which may then reach toxic values.</li>
	<li>Methotrexate: NSAIDs may accentuate the haematologic toxicity of methotrexate.</li>
	<li>Intrauterine contraceptive devices: NSAIDs appear to decrease the efficacy of intrauterine contraceptive devices.</li>
</ul>