<p><strong>Parenteral-</strong></p>

<p><strong>Chemotherapy-induced neutropenia</strong>:&nbsp;5 mcg/kg daily as a single daily SC inj, as a continuous IV or SC infusion, or as a daily IV infusion over 15-30 minutes, starting not<br />
<br />
<strong>Bone marrow transplantation</strong>:&nbsp;10 mcg/kg daily by IV infusion over 30 min or 4 hr or continuous IV or SC infusion over 24 hr. Adjust according to response.</p>

<p><br />
<strong>Subcutaneous-</strong></p>

<p><strong>Mobilisation of peripheral blood progenitor cells for autologous peripheral blood stem cell transplantation</strong>:&nbsp;10 mcg/kg daily, as a single inj or by continuous infusion, for 4-7 days until the last leucapheresis procedure. If it is given after myelosuppressive chemotherapy: 5 mcg/kg daily by inj; given from the 1st day after chemotherapy completion until expected neutrophil nadir is passed and neutrophil count has returned to normal range, so that leucapheresis can be performed.<br />
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<strong>Congenital neutropenia</strong>:&nbsp;12 mcg/kg daily in single or divided doses. Adjust according to response. In patients with cyclic or idiopathic neutropenia: 5 mcg/kg daily in single or divided doses. Adjust according to response.<br />
<br />
<strong>HIV infection and persistent neutropenia</strong>: Initially, 1 mcg/kg daily. Dose may be increased to 4 mcg/kg daily until normal neutrophil count is achieved. Maintenance: 300 mcg daily. Max: 4 mcg/kg daily.</p>