<p>Simvastatin should not be used in-</p>

<ul>
	<li>Active liver disease</li>
	<li>Pregnant and breast feeding mother</li>
	<li>Women of child bearing age unless they have been adequately protected by contraception</li>
	<li>Hypersensitivity to any component of the preparation</li>
	<li>Patients with the homozygous familial hypercholesterolemia who have a complete absence of LDL receptors</li>
</ul>