<p>Methimazole is administered orally. The total daily dosage is usually given in 3 divided doses at approximately 8 hour intervals.<br />
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<strong>Adults</strong>: The initial daily dosage is 15 mg for mild hyperthyroidism, 30 to 40 mg for moderately severe hyperthyroidism, and 60 mg for severe hyperthyroidism, divided into 3 doses at 8 hour intervals. The maintenance dosage is 5 to 15 mg daily.<br />
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<strong>Pediatric</strong>: Initially, the daily dosage is 0.4 mg/kg of body weight divided into 3 doses and given at 8 hour intervals. The maintenance dosage is approximately 1/2 of the initial dose.<br />
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<strong>Use in children &amp; adolescents</strong>: Because of post-marketing reports of severe liver injury in pediatric patient treated with propylthiouracil, Methimazole is the preferred choice when an antithyroid drug is required for a pediatric patient.</p>