<p><strong>Oral</strong>: The usual dose is 300 mg to 2 grams, 1 to 4 times daily.<br />
<br />
<strong>Intravenous&nbsp;</strong>(Severe metabolic acidosis):</p>

<ul>
	<li><strong>Adult:</strong>&nbsp;By slow inj of a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). For correction of acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given.</li>
	<li><strong>Elderly:</strong>&nbsp;Dosage adjustments may be required.</li>
</ul>