<p>Children under 18 years: Should be given only on medical advice.<br />
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Children and adolescents: Agomelatine is not recommended in the treatment of depression in patients .<br />
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Use in the elderly: Efficacy has not been clearly demonstrated in the elderly (65 years). Only limited clinical data is available on the use of Agomelatine in elderly patients 65 years with major depressive episodes. Therefore, caution should be exercised when prescribing Agomelatine to these patients.</p>