<p>The mode of action of riluzole is unknown. Its pharmacological properties include the following, some of which may be related to its effect:</p>

<ul>
	<li>An inhibitory effect on glutamate release (activation of glutamate reuptake),</li>
	<li>Inactivation of voltage-dependent sodium channels,&nbsp;</li>
	<li>Ability to interfere with intracellular events that follow transmitter binding at excitatory amino acid receptors.</li>
</ul>