<p>Treatment of Osteoporosis in Postmenopausal Women: The recommended dosage is-</p>

<ul>
	<li>70 mg alendronate and 2800 IU vitamin D3 or</li>
	<li>70 mg alendronate and 5600 IU vitamin D3 tablet once weekly.</li>
	<li>For most osteoporotic women, the appropriate dose is 70 mg alendronate and 5600 IU vitamin D3 once weekly.</li>
</ul>

<p>Treatment to Increase Bone Mass in Men with Osteoporosis: The recommended dosage is-</p>

<ul>
	<li>70 mg alendronate and 2800 IU vitamin D3 or</li>
	<li>70 mg alendronate and 5600 IU D3 tablet once weekly.</li>
	<li>For most osteoporotic men, the appropriate dose is 70 mg alendronate and 5600 IU vitamin D3 once weekly.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>To permit adequate absorption, Alendronate &amp; Colecalciferol must be taken at least 30 minutes before the first food, beverage or medication of the day with plain water only. Other beverages (including mineral water), food and some medications are likely to reduce the absorption of Alendronate. To facilitate delivery to the stomach and thus to reduce the potential for esophageal irritation, Alendronate &amp; Colecalciferol tablet should only be swallowed upon rising for the day with a full glass of water. Patients should not lie down for at least 30 minutes after taking Alendronate until after their first food of the day. Alendronate &amp; Colecalciferol should not be taken at bed time.</p>