<p>Carefully consider the potential benefits &amp; risks of this tablet &amp; other treatment options before deciding to use this tablet. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. If a dose of Esomeprazole lower than a total daily dose of 40 mg is more appropriate, a different treatment should be considered.<br />
<br />
Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis-</p>

<ul>
	<li><strong>Adults</strong>: One tablet twice daily of either: 375 mg naproxen/20 mg of esomeprazole; or 500 mg naproxen/20 mg of esomeprazole</li>
</ul>

<p>Juvenile Idiopathic Arthritis in Adolescent Patients 12 Years of Age &amp; Older-</p>

<ul>
	<li><strong>Weight greater than 50 kg</strong>: 375 mg naproxen/20 mg of esomeprazole; or 500 mg naproxen/20 mg of esomeprazole</li>
	<li><strong>Weight 38 kg to less than 50 kg</strong>: One tablet twice daily of 375 mg naproxen/20 mg of esomeprazole.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Do not split, chew, crush or dissolve the tablet. This tablet is to be taken at least 30 minutes before meals.</p>