<p><strong>Adults and adolescents over 16 years (prophylactic management in severe asthma)</strong>: 0.5-2 mg twice daily. The recommended initial dose is 2 mg twice daily. The dosage should then be adjusted until control is achieved or reduced to the minimum effective dose according to the individual response.<br />
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<strong>Children and adolescents 4 to 16 years of age (treatment of acute exacerbations of asthma)</strong>: 1 mg twice daily.</p>