<p>Pralidoxime chloride is indicated as an antidote:</p>

<ul>
	<li>In the treatment of poisoning due to those pesticides and chemicals (e.g., nerve agents) of the organophosphate class which have anticholinesterase activity and</li>
	<li>In the control of overdosage by anticholinesterase drugs used in the treatment of&nbsp;myasthenia gravis.</li>
</ul>

<p>The principal indications for the use of Pralidoxime chloride are muscle weakness and respiratory depression. In severe poisoning, respiratory depression may be due to muscle weakness.</p>