<p>Major Depressive Disorder (MDD)-</p>

<ul>
	<li><strong>Starting Dose</strong>: 40 mg/day to 60 mg/day</li>
	<li><strong>Target Dose</strong>: Acute: 40 mg/day (20 mg twice daily) to 60 mg/day (once daily or as 30 mg twice daily); Maintenance: 60 mg/day</li>
	<li><strong>Maximum Dose</strong>: 120 mg/day</li>
</ul>

<p>Generalized Anxiety Disorder (GAD)-</p>

<ul>
	<li><strong>Starting Dose</strong>: 60 mg/day</li>
	<li><strong>Target Dose</strong>: 60 mg/day (once daily)</li>
	<li><strong>Maximum Dose</strong>: 120 mg/day</li>
</ul>

<p>Diabetic Peripheral Neuropathic Pain (DPNP)-</p>

<ul>
	<li><strong>Starting Dose</strong>: 60 mg/day</li>
	<li><strong>Target Dose</strong>: 60 mg/day (once daily)</li>
	<li><strong>Maximum Dose</strong>: 60 mg/day</li>
</ul>

<p>Fibromyalgia-</p>

<ul>
	<li><strong>Starting Dose</strong>: 30 mg/day</li>
	<li><strong>Target Dose</strong>: 60 mg/day (once daily)</li>
	<li><strong>Maximum Dose</strong>: 60 mg/day</li>
</ul>

<p>Chronic Musculoskeletal Pain-</p>

<ul>
	<li><strong>Starting Dose</strong>: 30 mg/day</li>
	<li><strong>Target Dose</strong>: 60 mg/day (once daily)</li>
	<li><strong>Maximum Dose</strong>: 60 mg/day</li>
</ul>

<p>Some patients may benefit from starting at 30 mg once daily. There is no evidence that doses greater than 60 mg/day confers an additional benefit, while some adverse reactions were observed to be dose-dependent. A gradual dose reduction is recommended to avoid discontinuation symptoms.</p>

<p><a href="https://medex.com.bd/news/104/danger-of-taking-medication-without-doctors-advice" target="_blank"><em>* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন</em></a>&#39;</p>