<p><strong>Skin burning</strong>: Serious burns from either UVA or sunlight (even through window glass) can result if the recommended dosage of the drug and/or exposure schedules are not maintained.<br />
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<strong>Carcinogenicity</strong>: The increasing risk of carcinoma appears great among patients who are fair skinned or had pre PUVA exposure or prolong treatment with tar UVB, ionizing radiation or arsenic.<br />
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<strong>Cataractogenicity</strong>: Among patients using proper eye protection, there is no evidence for a significantly increased risk of cataracts in association with PUVA therapy.<br />
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Patients must not sunbathe during the 24 hours prior to Methoxsalen ingestion and UV exposure.</p>