<p><strong>Newly Diagnosed Glioblastoma Multiforme</strong>: Temozolomide is indicated for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with&nbsp;radiotherapy&nbsp;and then as maintenance treatment.<br />
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<strong>Refractory Anaplastic Astrocytoma</strong>: Temozolomide is indicated for the treatment of adult patients with refractory anaplastic astrocytoma, i.e., patients who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.</p>