<p><strong>Rifampin</strong>: Because of decreased concentrations, increasing Brivaracetam dosage in patients on concomitant rifampin is recommended.<br />
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<strong>Carbamazepine</strong>: Because of increased exposure to carbamazepine metabolite, if tolerability issues arise, consider reducing carbamazepine dosage in patients on concomitant Brivaracetam.<br />
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<strong>Phenytoin</strong>: Because phenytoin concentrations can increase, phenytoin levels should be monitored in patients on concomitant Brivaracetam.<br />
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<strong>Levetiracetam</strong>: Brivaracetam had no added therapeutic benefit when co-administered with levetiracetam.</p>