<p>Use of isoniazid should be carefully monitored in the following:</p>

<ul>
	<li>Daily users of alcohol. Daily ingestion of alcohol may be associated with a higher incidence of isoniazid hepatitis.</li>
	<li>Patients with active chronic liver disease or severe renal dysfunction.</li>
	<li>Age &gt;35.</li>
	<li>Concurrent use of any chronically administered medication.</li>
	<li>History of previous discontinuation of isoniazid.</li>
	<li>Existence of peripheral neuropathy or conditions predisposing to neuropathy. Pregnancy.</li>
	<li>Injection drug use.</li>
	<li>Women belonging to minority groups, particularly in the post-partum period.</li>
	<li>HIV seropositive patients.</li>
</ul>