<p>The dosage and duration of therapy shall be established depending on type, severity of infection and the condition of the patient. The recommended daily dosage is as follows-<br />
<br />
Adults:</p>

<ul>
	<li>The usual dose is 500 mg to 1 gm by intravenous administration every 8 hours.</li>
	<li>Pneumonia, urinary tract infections, gynaecological infections such as endometritis, pelvic inflammatory disease, skin and skin structure infections: 500 mg IV every 8 hours.</li>
	<li>Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patients and septicaemia: 1 g IV every 8 hours.</li>
	<li>Intra-abdominal infections: 500 mg to 1 gm every 8 hours.</li>
	<li>Cystic fibrosis: Upto 2 gm every 8 hours.</li>
	<li>Meningitis: 2 gm IV every 8 hours.</li>
</ul>

<p>Children:</p>

<ul>
	<li>3 months to 12 years: 10 to 40 mg/kg intravenously every 8 hours depending on type and severity of infection, susceptibility of the pathogens and the condition of the patient.</li>
	<li>Intra-abdominal infections: 20 mg/kg every 8 hours.</li>
	<li>Cystic fibrosis (4-18 years): 25-40 mg/kg every 8 hours.</li>
	<li>Meningitis: 40 mg/kg IV every 8 hours.</li>
	<li>Febrile neutropenia: 20 mg/kg every 8 hours.</li>
	<li>Children over 50 kg weight: use adult dosage.</li>
	<li>There is no experience in children with hepatic or renal impairment.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Meropenem should be administered by intravenous Infusion over approximately 15-30 minutes or as intravenous bolus (5 to 20 ml) over approximately 3-5 minutes</p>