<p>Hypertension:</p>

<ul>
	<li><strong>Recommended starting dose</strong>: 0.5 mg (in the evening), twice or thrice daily for 3 to 7 days. This dose should be increased to 1 mg twice or three times daily for a further 3 to 7 days. Thereafter, the daily dose should be increased gradually as determined by the patient&#39;s response to the blood pressure lowering effect. Most patients are likely to be maintained on a dosage regimen of Prazosin alone of up to 15 mg daily in divided doses.</li>
	<li><strong>Maximum dose</strong>: 20 mg in divided doses.</li>
</ul>

<p>Patients receiving other antihypertensive therapy but with inadequate&nbsp;control:</p>

<ul>
	<li>The dosage of the other drug should be reduced to a maintenance level and Prazosin initiated at 0.5 mg in the evening, then continuing with 0.5 mg twice or three times daily.</li>
	<li>Subsequent dosage increases should be made gradually depending upon the patient&#39;s response.</li>
</ul>

<p>Congestive heart failure:</p>

<ul>
	<li><strong>The recommended starting dose</strong>: 0.5 mg two, three or four times daily, increasing to 4 mg in divided doses. Dosage should be adjusted according to the patient&#39;s response, based on careful monitoring of cardiopulmonary signs and symptoms.</li>
	<li><strong>Usual daily maintenance dosage</strong>: 4 mg to 20 mg in divided doses.</li>
</ul>

<p>Raynaud&#39;s disease:</p>

<ul>
	<li><strong>The recommended starting dosage</strong>: 0.5 mg twice daily given for a period of 3 to 7 days and should be adjusted according to the patient&#39;s clinical response.</li>
	<li><strong>Usual maintenance dosage</strong>: 1 mg or 2 mg twice daily.</li>
</ul>

<p>Benign prostatic hyperplasia:</p>

<ul>
	<li><strong>The recommended dosage</strong>: 0.5 mg twice daily for a period of 3 to 7 days, with the initial dose administered in the evening. The dosage should then be adjusted according to clinical response.</li>
	<li><strong>The usual&nbsp;maintenance dosage</strong>: 2 mg twice daily.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>May be taken with or without food. Starting dose is best taken within dinner, at least 2-3 hr before retiring. Maintenance doses may be taken with or without meals.</p>