<p><strong>Treatment of postmenopausal osteoporosis, to reduce the risk of vertebral fractures. Treatment of&nbsp;established postmenopausal osteoporosis, to reduce the risk of hip fractures</strong>: The recommended&nbsp;dose is Risedronate Sodium 5 mg once daily or Risedronate Sodium 35 mg once weekly on the same day each week or Risedronate Sodium 150 mg once monthly.&nbsp;<br />
<br />
<strong>Prevention of osteoporosis in postmenopausal women with increased risk of osteoporosis</strong>: The&nbsp;recommended dose is Risedronate Sodium 5 mg once daily.&nbsp;<br />
<br />
<strong>To maintain or increase bone mass in postmenopausal women undergoing long-term (more than&nbsp;3 months):&nbsp;</strong>Systemic corticosteroid treatment at doses 7.5 mg/day prednisone or equivalent. The&nbsp;recommended dose is Risedronate Sodium 5 mg once daily.&nbsp;<br />
<br />
<strong>Treatment of osteoporosis in men at high risk of fractures</strong>: The recommended dose is Risedronate Sodium 35 mg once weekly. The tablet should be taken on the same day&nbsp;each week.</p>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>The absorption of Risedronate Sodium is affected by food, thus to ensure adequate absorption patients should take Risedronate tablets at least 30 minutes before the first food,&nbsp;other medicinal product or drink (other than plain water) of the day. In the particular instances&nbsp;that before breakfast dosing is not practical, Risedronate 5 mg tablet can be taken between meals or in&nbsp;the evening at the same time everyday, with strict adherence to the following instructions, to&nbsp;ensure Risedronate Sodium tablet is taken on an empty stomach-Between meals:<br />
<br />
Risedronate&nbsp;Sodium tablet should be taken at least 2 hours before and at least 2 hours after any food,&nbsp;medicinal product or drink (other than plain water). In the evening:<br />
<br />
Risedronate Sodium tablet&nbsp;should be taken at least 2 hours after the last food, medicinal product or drink (other than plain&nbsp;water) of the day.&nbsp;If a dose is missed: Risedronate 5 mg tablet: If an occasional dose is missed, Risedronate 5 mg tablet can be&nbsp;taken before breakfast, between meals, or in the evening according to the instructions above.<br />
<br />
<strong>Risedronate 35 mg tablet</strong>: Patients should be instructed that if a dose is missed, just take one Risedronate&nbsp;35 mg tablet on the morning after remember. Patients should then return to taking one tablet&nbsp;once a week on the day the tablet is normally taken. Two tablets should not be taken on the&nbsp;same day.<br />
<br />
<strong>Risedronate 150 mg tablet</strong>: Patient should be instructed that if a dose is missed and the next month&rsquo;s&nbsp;schedule dose is more than 7 days away, then should take the missed tablet in the morning after&nbsp;the day it is remembered. Patients should then return to taking one tablet once a month normally taken.The tablet must be swallowed whole and not sucked or chewed. To aid delivery of&nbsp;the tablet to the stomach Risedronate tablet is to be taken while in an upright position with a glass of&nbsp;plain water (120 ml or more). Patients should not lie down for 30 minutes after taking the tablet. Supplemental calcium and vitamin D should be considered if the dietary intake is inadequate.</p>