<p><strong>Pediatric Use</strong>: STENDRA is not indicated for use in pediatric patients. Safety and efficacy in patients below the age of 18 years has not been established.<br />
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<strong>Geriatric Use</strong>: Of the total number of subjects in clinical studies of avanafil, approximately 23% were 65 and over. No overall differences in efficacy and safety were observed between subjects over 65 years of age compared to younger subjects; therefore no dose adjustment is warranted based on age alone. However, a greater sensitivity to medication in some older individuals should be considered<br />
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<strong>Renal &amp;&nbsp;hepatic impairment patients</strong>: Do not use in patients with severe renal &amp; hepatic impairment.</p>