<p>The first dose should be infused over at least 6 hours; doses on subsequent days should be infused over at least 4 hours.<br />
<br />
Premedication with corticosteroids, acetaminophen, and/or an antihistamine prior to each infusion is recommended.<br />
<br />
The Anti-Thymocyte Globulin dose should be reduced by one half if the white blood cell (WBC) count is between 2,000 and 3,000 cells/mm3 or if the platelet count is between 50,000 and 75,000 cells/mm3. Stopping Anti-Thymocyte Globulin treatment should be considered if the WBC count falls below 2,000 cells/mm3 or if the platelet count falls below 50,000 cells/mm3<br />
&nbsp;</p>

<ul>
	<li><strong>Prophylaxis of acute rejection</strong>: 1.5 mg/kg of body weight administered daily for 4 to 7 days</li>
	<li><strong>Treatment of acute rejection</strong>: 1.5 mg/kg of body weight administered daily for 7 to 14 days</li>
</ul>