<p>The usual adult oral dosage of Tetracycline is 1-2 g daily given in 2-4 divided doses. The usual oral dosage of Tetracycline for children older than 8 years of age in 25-50 mg/kg daily given in 2-4 divided doses. Alternatively some clinicians recommended that children should receive 0.6-1.2 g/m2 daily.<br />
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Tetracycline should be taken preferably one hour before or 2 hours after meals.<br />
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Some specific indications along with some information on dosage is given below:<br />
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<strong>Acne vulgaris</strong>: 250 mg four times daily or 500 mg 12 hourly for 1 week; 125-250 mg for several weeks or months.&nbsp;Duration of therapy is determined by individual progress<br />
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<strong>Acute&nbsp;staphylococcal infections</strong>: 1-2 g daily in divided&nbsp;doses for 10-14 days<br />
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<strong>Acute streptococcal infections</strong>:&nbsp;1-2 g daily in divided doses for 10 days.&nbsp;Prolonged therapy is needed to avoid risk of rheumatic fever or glomerulonephritis<br />
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<strong>Amoebiasis</strong>:&nbsp;1 g daily in four divided doses or 500 mg 12 hourly for 7 days.&nbsp;Given in association with amoebicidal agents<br />
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<strong>Brucellosis</strong>: 500 mg four times daily plus 1 g streptomycin twice daily for 1 week ; then 500 mg four times daily (no streptomycin) for 1 week.&nbsp;Prolonged therapy is necessary to avoid relapse<br />
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<strong>Subacute bacterial endocarditis</strong>:&nbsp;1-2 g daily in divided doses for 6 weeks.&nbsp;Usually given in combination with a bactericidal agent<br />
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<strong>Syphilis</strong>:&nbsp;Total 30-40 g given in divided doses over 10-15 days.&nbsp;Serology and spinal fluid examination should follow the administration of tetracycline</p>