<p>Nystatin cream should not be used for the treatment of systemic, oral, intravaginal or ophthalmic infections. If irritation or sensitization develops, treatment should be discontinued and appropriate measures taken as indicated. It is recommended that KOH smears, cultures, or other diagnostic methods be used to confirm the diagnosis of&nbsp;cutaneous&nbsp;or mucocutaneous candidiasis and to rule out infection caused by other pathogens.</p>