<p><strong>Dosing for Parkinson&#39;s disease</strong>: The recommended starting dose for Parkinson&#39;s disease is 0.25 mg three times daily. Based on individual patient therapeutic response and tolerability, if necessary, the dose should then be titrated with weekly increments as described below. Maximum recommended total daily dose of 24 mg (8 mg three times daily).</p>

<ul>
	<li><strong>Week 1</strong>: 0.25 mg 3 times daily. Total Daily Dose 0.75 mg</li>
	<li><strong>Week 2</strong>: 0.5 mg 3 times daily. Total Daily Dose 1.50 mg</li>
	<li><strong>Week 3</strong>: 0.75 mg 3 times daily. Total Daily Dose 2.25 mg</li>
	<li><strong>Week 4</strong>: 1 mg 3 times daily. Total Daily Dose 3 mg</li>
</ul>

<p><strong>Dosing for Restless Legs Syndrome</strong>: The recommended adult starting dose for RLS is 0.25 mg once daily 1 to 3 hours before bedtime. After 2 days, if necessary, the dose can be increased to 0.5 mg once daily, and to 1 mg once daily at the end of the first week of dosing, then as shown below as needed to achieve efficacy. Titration should be based on individual patient therapeutic response and tolerability, up to a maximum recommended dose of 4 mg daily.</p>

<ul>
	<li><strong>Days 1 and 2</strong>: 0.25 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 3-7</strong>: 0.5 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 2</strong>: 1 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 3</strong>: 1.5 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 4</strong>: 2 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 5</strong>: 2.5 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 6</strong>: 3 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
	<li><strong>Days 7</strong>: 4 mg, 1 to 3 hours before bedtime, to be taken once daily</li>
</ul>