<p>Oxaprozin, the&nbsp;potassium&nbsp;salt of oxaprozin, is a nonsteroidal anti-inflammatory drug (NSAID), which dissociates into the active moiety oxaprozin&nbsp;in vivo. Oxaprozin has&nbsp;analgesic, anti-inflammatory, and&nbsp;antipyretic&nbsp;properties.<br />
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The mechanism of action of Oxaprozin, like that of other NSAIDs, is not completely understood but involves inhibition of&nbsp;cyclooxygenase&nbsp;(COX-1&nbsp;and&nbsp;COX-2).<br />
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Oxaprozin is a potent inhibitor of&nbsp;prostaglandin&nbsp;synthesis&nbsp;in vitro. Oxaprozin concentrations reached during therapy have produced&nbsp;in vivo&nbsp;effects. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal models. Prostaglandins are mediators of inflammation. Because oxaprozin potassium is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.</p>