<p><strong>Moderate and Severe Renal Impairment</strong>: Recommended starting dose is 20 mg per day, and the maximum recommended dose is 80 mg per day .<br />
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<strong>Moderate and Severe Hepatic Impairment</strong>: Recommended starting dose is 20 mg per day. The maximum recommended dose is 80 mg per day in moderate hepatic impairment and 40 mg per day in severe hepatic impairment.</p>