<p><strong>Children use</strong>: Safety and effectiveness in children have not been established.<br />
<br />
<strong>Geriatric use</strong>: Reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.</p>