<p>The dosage of insulin aspart must be individualized.<br />
<br />
<strong>Subcutaneous injection</strong>: insulin aspart should generally be given immediately (within 5-10 minutes) prior to the start of a meal.<br />
<br />
<strong>Use in pumps</strong>: Change the insulin aspart in the reservoir at least every 6 days, change the infusion set, and the infusion set insertion site at least every 3 days. insulin aspart should not be mixed with other insulins or with a diluent when it is used in the pump.<br />
<br />
<strong>Intravenous use</strong>: insulin aspart should be used at concentrations from 0.05 U/mL to 1.0 U/mL insulin aspart in infusion systems using polypropylene infusion bags. insulin aspart has been shown to be stable in infusion fluids such as 0.9% sodiumchloride.</p>

<p><strong>Administration</strong></p>

<p>Before going for administration of Biphasic Insulin Aspart (rDNA) please follow the below mentioned check list:</p>

<ul>
	<li>Insulin syringe of the right size (100 units/ml)</li>
	<li>Prescribed type of insulin injection</li>
	<li>Check the expiry date on Biphasic Insulin Aspart (rDNA) vial</li>
	<li>Ensure that the flip off cap on the Biphasic Insulin Aspart (rDNA) vial is intact</li>
</ul>

<p>After that follow the below mentioned instructions:</p>

<ul>
	<li>Wash your hands carefully. Shake or roll the vial 10 times to completely Mix the insulin.</li>
	<li>lnspect the vial. Vial should appear white and cloudy after mixing.</li>
	<li>When using a new vial, flip off the plastic protective cap, but do not remove the stopper. The tip of the vial should be wiped with an alcohol swab.</li>
	<li>Draw air into the syringe equal to your insulin dose.</li>
	<li>Insert needle into vial through rubber top &amp; push plunger to empty the air into the vial.</li>
	<li>Turn the bottle and syringe upside down. Hold the bottle and syringe firmly in one hand and shake gently. Make sure that the tip of the needle is in the liquid; withdraw the correct dose of insulin into the syringe.</li>
	<li>Before removing the needle from the vial, check the insulin syringe for air bubbles, which reduces the amount of insulin in it, if bubbles are present, hold the insulin straight up and tap its side until the bubbles float to the top. Push them out with the plunger and withdraw the correct dose again.</li>
	<li>Lightly pinch up the skin, holding the syringe like a pencil.</li>
	<li>Insert the needle into the skin &amp; push the plunger slowly. Make sure that the needle is all the way in.</li>
	<li>Wait for 5 seconds &amp; pull out the syringe. Do not rub the area.</li>
</ul>