<p><strong>Elderly</strong>: Amisulpride should be used with particular caution because of a possible risk of hypotension or sedation.<br />
<br />
<strong>Children</strong>: The efficacy and safety of amisulpride from puberty to the age of 18 years have not been established: there are limited data available on the use of amisulpride in adolescents in schizophrenia. Therefore, the use of amisulpride from puberty to the age of 18 years is not recommended. In children up to puberty, the use of amisulpride is contraindicated<br />
<br />
<strong>Use in hepatic impairment</strong>: The impact of hepatic impairment on hepatic metabolism and hepato-biliary excretion of amisulpride has not been studied. Amisulpride should be used with caution in patients with moderate or severe hepatic impairment.<br />
<br />
<strong>Use in renal impairment</strong>: Amisulpride is eliminated by the renal route. In cases of renal insufficiency, the dose should be decreased and intermittent treatment should be considered</p>