<p><strong>Pediatric Use</strong>: Safety and effectiveness of Pimavanserin have not been established in pediatric patients.<br />
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<strong>Geriatric Use</strong>: No dose adjustment is required for elderly patients.<br />
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<strong>Renal Impairment</strong>: No dosage adjustment for Pimavanserin is needed in patients with mild to moderate (CrCL &ge;30 mL/min, Cockcroft-Gault) renal impairment.<br />
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<strong>Hepatic Impairment</strong>: Use of Pimavanserin is not recommended in patients with hepatic impairment. Pimavanserin has not been evaluated in this patient population.</p>