<p><strong>Polymenorrhoea</strong>: 1 tablet daily on days 14-25 of the cycle.<br />
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<strong>Premenstrual syndrome</strong>: 1 tablet daily on days, 4-25 of the cycle.<br />
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<strong>Endometriosis</strong>: 1-2 tablets daily for at least 6 months.<br />
<br />
<strong>Selected cases of endometrial carcinoma</strong>: 6-10 tablets daily for prolonged periods.<br />
<br />
<strong>Benign breast disease</strong>: 1 tablet daily on days 14-25 of the cycle for at least 3-4 months.<br />
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<strong>Menorrhagia and metrorrhagia</strong>: 1 tablet daily on days 14-25 of the cycle cease within a few days after the start of the treatment. Treatment is repeated during the next 3 menstrual cycles with 1 tablet daily on days 14-25 of each cycle. Further diagnostic procedures are necessary if the complaints do not disappear during or after this treatment.<br />
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<strong>Selected cases of primary and secondary amenorrhoea and oligomenorrhoea</strong>: Treatment should start with the administration of an estrogen, e.g. 0.02-0.05 mg ethinylestradiol per day for 25 days. In conjunction with this, 1 tablet daily of Lynestrenol is administered on days 14-25. After cessation of treatment, a withdrawal bleeding usually occurs within 3 days. Treatment is resumed (second cycle) starting on day 5 of this withdrawal bleeding with the estrogen given on days 5-25 of the cycle and again with 1 tablet daily of Lynestrenol on days 14-25. This treatment should be repeated for at least another cycle.<br />
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<strong>Suppression of menstruation ovulation and ovulation pain dysmenorrhoea</strong>: Treatment with 1 tablet daily should start preferably on day 1, but no later than day 5 of the cycle The treatment can be continued for many months (without tablet-free days). If in spite of treatment, a breakthrough bleeding occurs, the dosage should be increased to 2 or 3 tablets daily for 3-5 days.<br />
<br />
<strong>Postponement of menstruation</strong>: Treatment with 1 tablet daily should start preferably 2 weeks before the expected onset of menstruation. If treatment is started less than 1 week before the expected onset of menstruation the dosage should be 2-3 tablets per day. However, in that case a delay of more than 1 week is undesirable. The risk of breakthrough bleeding increases if treatment is started later. Therefore, treatment should not be started later than 3 days before the expected onset of menstruation.<br />
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<strong>As an adjunct to estrogen therapy in pre-and postmenopause in order to avoid endometrial hyperplasia</strong>: 1/2-1 tablet daily for 12-15 days per month, e.g. for the first 2 weeks of every calendar month; the estrogen may be administered daily without tablet-free intervals at the lowest effective dose.</p>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Lynestrenol tablets should be taken orally with some fluid.</p>