<p>Sodium Valproate tablets may be given once or twice daily. Sodium Valproate syrup should be given in divided doses.<br />
<br />
Epilepsy-</p>

<ul>
	<li><strong>Adults</strong>: Initially 600 mg daily given in 2 divided doses, preferably after food, increasing by 200 mg/day at 3-day intervals to a maximum of 2.5 g daily in divided doses until control of seizure is achieved. Usual maintenance dose is 1-2 g daily (20-30 mg/kg daily)</li>
	<li><strong>Children (up to 20 kg)</strong>: Initially 20 mg/kg daily in divided doses, may be increased provided plasma concentrations monitored (above 40 mg/kg daily also monitor clinical chemistry and hematological parameters).</li>
	<li><strong>Children (over 20 kg)</strong>: Initially 400 mg daily in divided doses increased until control (usually in the range of 20-30 mg/kg daily) Maximum 35 mg/kg daily.</li>
</ul>

<p><strong>Febrile convulsion</strong>: 20-30 mg/kg/day in 3 divided doses.<br />
<br />
<strong>Bipolar disorder</strong>: Initially 20-30 mg/kg/day in 2-3 divided doses; adjust dosage in 3-5 days. Maintenance dosage is 1000-2000 mg/day.<br />
<br />
<strong>Prophylaxis of migraine</strong>: 300 mg twice daily, although some may require 1000 mg daily.</p>