<p>This is a soluble insulin product consisting of the basal insulin degludec and the rapid-acting prandial insulin aspart.<br />
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This is to be dosed in accordance with the individual patient&#39;s needs. Dose-adjustments are recommended to be primarily based on fasting plasma glucose measurements.<br />
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<strong>Patients with type 2 diabetes mellitus</strong>: The recommended total daily starting dose is 10 units with meal(s) followed by individual dosage adjustments.<br />
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<strong>Patients with type 1 diabetes mellitus</strong>: The recommended starting dose is 60-70% of the total daily insulin requirements. This is to be used once-daily at meal-time in combination.</p>

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<p>This can be administered once- or twice-daily with the main meal(s). When needed, the patient can change the time of administration as long as this insulin is dosed with the largest meal when taken once daily.<br />
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In patients with type 2 diabetes mellitus this insulin can be administered alone, in combination with oral anti-diabetic medicinal products, and in combination with bolus insulin.<br />
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In type 1 diabetes mellitus, this insulin is combined with short-/rapid-acting insulin at the remaining meals.</p>

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