<p><strong>Dorzolamide,</strong>&nbsp;a carbonic anhydrase inhibitor, has actions similar to acetazolamide. By inhibiting carbonic anhydrase in the ciliary processes of the eye, dorzolamide decreases aqueous humor secretion. Used together, there is additional intraocular pressure reduction compared to using either component alone, but the reduction is not as much as concomitant admin of dorzolamide tid and timolol bid.<br />
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<strong>Timolol maleate,</strong>&nbsp;a nonselective &beta;-adrenergic blocker, reduces aqueous humor formation.</p>