<p>Oral administration:</p>

<ul>
	<li><strong>Adult</strong>: 250 mg four times daily. Dosage may be doubled in severe infections. In osteomyelitis and endocarditis, up to 8 gm daily is used in 6-8 hourly divided doses.</li>
	<li><strong>Children (2-10 years)</strong>: 1/2 of adult dose.</li>
	<li><strong>Children (Under 2 years)</strong>: 1/4 of adult dose.</li>
</ul>

<p>Parenteral administration:<br />
Adult or Elderly:</p>

<ul>
	<li><strong>Intramuscular Injection</strong>: 250 mg four times daily.</li>
	<li><strong>Intravenous Injection</strong>: 250 mg-1 g four times daily by slow injection over 3 to 4 minutes or by intravenous infusion.</li>
	<li><strong>All systemic doses may be doubled in severe infections</strong>: doses up to 8 g daily have been suggested for endocarditis or osteomyelitis.</li>
</ul>

<p>Children:</p>

<ul>
	<li><strong>2-10 years</strong>: half of the adult dose.</li>
	<li><strong>Under 2 years</strong>: a quarter of the adult dose.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Oral doses should be administered 1 hour before meal.</strong></p>