<p>Adults-</p>

<ul>
	<li><strong>The usual dose</strong>: 500-1000 mg 3 times daily.</li>
	<li><strong>For prophylaxis</strong>: The mean recommended daily doses are 0.5-1 gm orally, 500 mg by the parenteral (intravenous or intramuscular) route.</li>
	<li><strong>For therapy of hemorrhagic manifestations</strong>: the oral dose increases to 1-3 gm given in divided doses: in cases of particular seriousness and urgency, begin by injecting an ampoule (500 mg) slowly by intravenous route and administer the necessary subsequent oral doses.</li>
</ul>

<p>Children-</p>

<ul>
	<li><strong>For prophylaxis</strong>: For every kg of body weight from 5-10 mg are orally administered daily in divided doses.</li>
	<li><strong>For therapeutic purposes</strong>: The oral doses are doubled (from 10 to 20 mg/kg), while the intravenous and intramuscular treatment is begun with 10 mg/kg (=0.5 ml every 5 kg) by the slow intravenous route, continuing the oral administration up to the required dose. Where it is more convenient (e.g. in small babies) the ampoules, diluted in a little sweetened water, maybe orally administered instead of the Capsules.</li>
</ul>

<p>Elderly patients: No reduction in dosage is necessary unless there is evidence of renal failure.</p>