<p>This should not be used with monoamine-oxidase inhibitor (MAOI), antidepressants (e.g. phenelzine). Prolonged use of paracetamol may enhance the effects of anti-clotting/ blood thinning medicines such as warfarin, leading to an increased risk of bleeding. Methionine may reduce the effect of levodopa. Metoclopramide and domperidone increase the rate of absorption of paracetamol from the gut. The absorption of paracetamol is decreased if cholestyramine is taken at the same time.</p>