<p>Impaired renal or liver function, DM, chronic alcoholism, undernourishment, history of gout, patients with convulsive disorders, acute porphyria. Elderly. Pregnancy &amp; lactation. Perform periodic blood counts &amp; liver function tests. Avoid use with soft contact lenses.<br />
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Children &lt;8 year or patients who are not able to communicate visual disturbances. Check visual ability before starting treatment &amp; monitor during treatment.</p>