<p>Hypersensitivity to rifampicin, isoniazid, pyrazinamide or ethambutol.<br />
<br />
<strong>Isoniazid</strong>: Previous isoniazid-associated hepatic injury; severe adverse reactions to isoniazid eg, fever, chills and arthritis; acute liver disease of any etiology, a history of previous hypersensitivity reaction to isoniazid including drug-induced hepatitis.</p>