<p>Renal Impairment-<br />
<br />
<strong>Osteoarthritis:</strong>&nbsp;Severe or on dialysis: 600 mg once daily. Increase to 1.2 g daily if needed.<br />
<strong>Rheumatoid arthritis:</strong>&nbsp;Severe or on dialysis: 600 mg once daily. Increase to 1.2 g daily if needed.</p>