<p><strong>Oral:&nbsp;</strong>Epilepsy:</p>

<ul>
	<li><strong>Adult:</strong>&nbsp;Initially, 3-4 mg/kg daily as single dose or in divided doses. Alternatively, 150-300 mg daily increased gradually to 600 mg daily if necessary. Maintenance: 200-500 mg daily.</li>
	<li><strong>Child:</strong>&nbsp;Initially, 5 mg/kg daily in 2-3 divided doses. Maintenance: 4-8 mg/kg daily in divided doses. Max dose: 300 mg daily.</li>
</ul>

<p><strong>Intravenous:&nbsp;</strong>Tonic-clonic status epilepticus:</p>

<ul>
	<li><strong>Adult:</strong>&nbsp;Adjunctive therapy with a benzodiazepine (e.g. diazepam): 10-15 mg/kg by slow inj or intermittent infusion at a max rate of 50 mg/min. Maintenance: 100 mg IV (or orally) given every 6-8 hr.</li>
	<li><strong>Child:</strong>&nbsp;Neonates: 20 mg/kg as a loading dose, then 2.5-5 mg/kg bid; 1 mth-12 yr: 18 mg/kg as a loading dose, then 2.5-5 mg/kg bid; &gt;12 yr: 18 mg/kg as a loading dose, then up to 100 mg 3-4 times daily.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Should be taken with food. When administering to patients on nasogastric or other enteral feeds, do not administer feeds 2 hr before or after a dose. Be consistent throughout therapy in relation to feed times. Do not switch dosage forms/brands w/o prior consideration.</p>