<p><strong>Infections</strong>: Serious infections have occurred. Caution should be exercised when considering the use of secukinumab in patients with a chronic infection or a history of recurrent infection. If a serious infection develops, discontinue secukinumab until the infection resolves.<br />
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<strong>Tuberculosis (TB)</strong>: Prior to initiating treatment with secukinumab, evaluate for TB.<br />
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<strong>Inflammatory Bowel Disease</strong>: Cases of inflammatory bowel disease were observed in clinical trials. Caution should be exercised when prescribing secukinumab to patients with inflammatory bowel disease.<br />
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<strong>Hypersensitivity Reactions</strong>: If an anaphylactic reaction or other serious allergic reaction occurs, discontinue secukinumab immediately and initiate appropriate therapy.</p>