<p><strong>Oral</strong>:<br />
Chronic bronchospasm:</p>

<ul>
	<li><strong>Adult</strong>: As hydrate: Initially, 225-450 mg bid, increased if necessary.</li>
	<li><strong>Child</strong>: &gt;3 yr: As modified-release hydrate: 12 mg/kg daily increased to 24 mg/kg daily in 2 divided doses after 1 wk.</li>
</ul>

<p><strong>Intravenous</strong>:<br />
Acute severe bronchospasm:</p>

<ul>
	<li><strong>Adult</strong>: Loading dose: 5 mg/kg (ideal body weight) or 250-500 mg (25 mg/ml) by slow inj or infusion over 20-30 min. Maintenance infusion dose: 0.5 mg/kg/hr. Max rate: 25 mg/min.</li>
	<li><strong>Child</strong>: Loading dose: same as adult dose. Maintenance dose: 6 mth-9 yr: 1 mg/kg/hr and 10-16 yr: 0.8 mg/kg/hr.</li>
	<li><strong>Elderly</strong>: Dose reduction may be necessary.</li>
	<li><strong>Hepatic impairment</strong>: Dose reduction may be necessary.</li>
</ul>

<p>&nbsp;</p>

<p><strong>Administration</strong></p>

<p>Tablets should be swallowed whole and not chewed because of the structure of the tablet.</p>