<p><strong>Urokinase injection is indicated in adults</strong>:</p>

<ul>
	<li>For the&nbsp;lysis&nbsp;of&nbsp;acute&nbsp;massive pulmonary emboli, defined as&nbsp;obstruction&nbsp;of blood flow to a&nbsp;lobe&nbsp;or multiple segments.</li>
	<li>For the lysis of pulmonary emboli accompanied by unstable hemodynamics, i.e., failure to maintain&nbsp;blood pressure&nbsp;without supportive measures.</li>
</ul>

<p>The&nbsp;diagnosis&nbsp;should be confirmed by objective means, such as pulmonary&nbsp;angiography&nbsp;or noninvasive procedures such as lung scanning.</p>