<p>Remarkable drug interactions of Rosuvastatin are-</p>

<ul>
	<li><strong>Cyclosporine</strong>: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be limited to 5 mg once daily.</li>
	<li><strong>Gemfibrosil</strong>: Combination should be avoided. If used together, Rosuvastatin dose should be limited to 10 mg once daily.</li>
	<li><strong>Lopinavir/Ritonavir or atazanavir/ritonavir</strong>: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be to 10 mg once daily.</li>
	<li><strong>Coumarin anticoagulants</strong>: Combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Rosuvastatin. INR should be monitored frequently until stable upon initiation or alteration of Rosuvastatin therapy.</li>
	<li><strong>Concomitant lipid-lowering therapies</strong>: Use with fibrates and niacin products may increase the risk of skeletal muscle effects.</li>
</ul>