<p>Long-term&nbsp;clinical trials&nbsp;have been conducted with dosages up to 200 mg of Bicalutamide daily and these dosages have been well tolerated. A single dose of Bicalutamide that results in symptoms of an overdose considered to be life threatening has not been established. There is no specific antidote; treatment of an overdose should be&nbsp;symptomatic.<br />
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In the management of an overdose with Bicalutamide, vomiting may be induced if the patient is alert. It should be remembered that, in this patient population, multiple drugs may have been taken.&nbsp;Dialysis&nbsp;is not likely to be helpful since Bicalutamide is highly protein bound and is extensively metabolized. General supportive care, including frequent monitoring of&nbsp;vital&nbsp;signs and close observation of the patient, is indicated.</p>