<p>For most patients, the starting dose is 100 mg taken approximately 30 minutes before sexual activity, on an as needed basis.&nbsp;Avanafil may be taken with or without food. Take Avanafil no more than once a day<br />
<br />
The dose may be increased to 200 mg or decreased to 50 mg based on efficacy and/or tolerability. Use the lowest dose that provides benefit<br />
<br />
Do not use Avanafil with strong CYP3A4 inhibitors. If taking a moderate CYP3A4 inhibitor, the dose should be no more than 50 mg in a 24-hour period. In patients on stable alpha-blocker therapy, the recommended starting dose of Avanafil is 50 mg</p>