<p><strong>Transplant patients:</strong><br />
Standard dosage for prophylaxis of renal rejection</p>

<ul>
	<li><strong>Adults</strong>: A dose of 1 g administered orally twice a day (daily dose of 2 g) is recommended for use in renal transplant patients.</li>
	<li><strong>Children (aged 3 months to 18 years)</strong>: Patients with a body surface area of 1.25 to 1.5 m2&nbsp;may be prescribed Mycophenolate Mofetil Tablets at a dose of 750 mg twice daily (1.5 g daily dose). Patients with a body surface area &gt;1.5 m2&nbsp;may be prescribed Mycophenolate Mofetil tablets at a dose of 1 gm twice daily (2 g daily dose).</li>
</ul>

<p>Standard dosage for prophylaxis of cardiac rejection-</p>

<ul>
	<li><strong>Adults</strong>: A dose of 1.5 g administered orally (over not less than 2 hour) twice a day (daily dose of 3 g) is recommended for use in cardiac transplant patients.</li>
	<li><strong>Children</strong>: no data are available for pediatric cardiac transplant patients.</li>
</ul>

<p>Standard dosage for prophylaxis of hepatic rejection-</p>

<ul>
	<li><strong>Adults</strong>: A dose of 1.5 g orally twice a day (daily dose of 3 g) is recommended for use in hepatic transplant patients</li>
	<li><strong>Children</strong>: no data are available for pediatric hepatic transplant patients.</li>
</ul>

<p>Standard dosage for treatment of first or refractory renal rejection-</p>

<ul>
	<li><strong>Adults</strong>: A dose of 1.5 g administered orally twice a day (daily dose of 3 g) is recommended for management of first or refractory rejection.</li>
	<li><strong>Children</strong>: no data are available for the treatment of first or refractory renal rejection in pediatric renal transplant patients.</li>
</ul>

<p><br />
<strong>Lupus nephritis patients:</strong><br />
Standard Dosage for Induction Therapy-</p>

<ul>
	<li><strong>Adults</strong>: A dose of 750 mg-1.5 g administered orally twice a day (daily dose of up to 3 g) is recommended</li>
	<li><strong>Children</strong>: A dose of 600 mg/m2&nbsp;administered orally twice a day (up to a maximum of 2 g daily) is recommended</li>
</ul>

<p>Standard Dosage for Maintenance Therapy-</p>

<ul>
	<li><strong>Adults</strong>: A dose of 500 mg-1 g administered orally twice a day is recommended</li>
	<li><strong>Children</strong>: A dose of 300 mg/m2&nbsp;administered orally twice a day is recommended</li>
</ul>

<p>Mycophenolate Mofetil should be used in combination with corticosteroids. Doses should be introduced gradually and adjusted according to clinical response. Therapeutic drug monitoring could help prevent sub-therapeutic exposure (Cmin&ge;3.0 mg/L or inter-dose AUC &ge;35 h*mg/L).</p>