<p>There is no clinical data on overdosage with this tablet.<br />
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<strong>Overdose of Naproxen</strong>: Significant naproxen overdosage may be characterized by lethargy, drowsiness, epigastric pain, abdominal discomfort, heartburn, indigestion, nausea, transient alteration in liver function, hypoprothrombinemia, renal dysfunction, metabolic acidosis, apnea, vomiting etc.<br />
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<strong>Overdose of Esomeprazole</strong>: The major signs of acute toxicity were reduced motor activity, changes in respiratory frequency, tremor and intermittent clonic convulsions etc.</p>