<ul>
	<li>Potent inhibitors of Cytochrome P450 3A4 (CYP3A4) (e.g., Ketoconazole)</li>
	<li>Recommended dose is Tofacitinib 5 mg once daily: One or more concomitant medications that result in both moderate inhibition of CYP3A4 and potent inhibition of CYP2C19 (e.g., fluconazole)</li>
	<li>Recommended dose is Tofacitinib 5 mg once daily Potent CYP inducers (e.g.Rifampin): May result in loss of or reduced clinical response.</li>
</ul>