<p>Fenticonazole is a potent broad-spectrum antimycotic agent. It exerts fungistatic and fungicidal actions on dermatophytes, pathogenic yeasts, dimorphous fungi and molds. In addition, Fenticonazole is active against gram-positive bacteria and is therefore indicated in mycoses associated with bacterial super infections. Fenticonazole is also active, both in vitro and in vivo, against Trichomonas vaginalis. Fenticonazole exerts its unique antimycotic action through following three ways:</p>

<ul>
	<li>Inhibiting the biosynthesis of ergosterol leading to the damage of fungal cell membrane.</li>
	<li>Causing certain changes in oxidative and peroxidative enzyme activities inside fungal cell. This leads to an intracellular build-up of toxic concentrations of hydrogen peroxide resulting in cell necrosis.</li>
	<li>Inhibiting the secretion of aspartic proteases (responsible for pathogenicity) by Candida albicans.</li>
</ul>

<p>The amount of Fenticonazole absorbed by the transcutaneous route is negligible.</p>