<p><strong>Renal &amp; hepatic impairment:</strong>&nbsp;A similar dose schedule can be followed for patients with renal or mild to moderate hepatic impairment as clearance of donepezil hydrochloride is not affected by these conditions.<br />
<br />
<strong>Use in children:</strong>&nbsp;There are no adequate and well controlled trials in document to safety and efficacy of Donepezil hydrochloride in any illness occurring in children. Donepezil is not recommended for use in children.</p>