<p><strong>Pregnancy:</strong>&nbsp;There are no adequate and well-controlled studies in pregnant women with this combination or its individual components. So, it should only be used if the potential benefit justifies the potential risk to the fetus.<br />
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<strong>Nursing mother:</strong>&nbsp;It is not known whether Pioglitazone and/or Metformin are secreted in human milk. Because many drugs are excreted in human milk, this combination should not be administered to a breastfeeding woman.</p>