<ul>
	<li>Strong cytochrome P450 3A4 inhibitors (e.g., ketoconazole): Use with caution. May cause systemic corticosteroid and cardiovascular effects.</li>
	<li>Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. May potentiate the effect of vilanterol on the vascular system.</li>
	<li>Beta-blockers: Use with caution. May block bronchodilatory effects of beta-agonists and produce severe bronchospasm.</li>
	<li>Diuretics: Use with caution. Electrocardiographic changes and/or hypokalemia associated with non&ndash;potassium-sparing diuretics may worsen with concomitant beta-agonists.</li>
	<li>Anticholinergics: May interact additively with concomitantly used anticholinergic medications. Avoid administration of this preparation with other anticholinergic-containing drugs.</li>
</ul>