<p>Advanced atherosclerotic disease, crush injury, septicemia or disseminated intravascular coagulation. Patients w/ history of CHD, liver disease, undergoing major surgery, at risk of thromboembolic phenomena or disseminated intravascular coagulation. Remote possibility of hypersensitivity to mouse IgG, bovine IgG &amp; other residual culture proteins. Monitor prothrombin time &amp; factor VII coagulant activity in factor VII deficient patients. Pregnancy &amp; lactation. Neonates.</p>