<p>2 years children &amp; Adult Dose:<br />
<br />
<strong>Chronic Iron overload:</strong>&nbsp;Initially, 20 mg/kg daily. Adjust dosage every 3-6 months as needed based on trends in serum ferritin concentrations (monitor monthly). Adjust dosage in increments of 5 or 10 mg/kg daily (up to maximum dosage of 30 mg/kg daily) according to the patient&rsquo;s clinical response and therapeutic goals. Consider temporarily interrupting therapy if serum ferritin concentrations are consistently &lt;500 mcg/L.</p>

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<p><strong>Administration</strong></p>

<p>Deferasirox must be taken once daily on an empty stomach at least 30 minutes before food, preferably at the same time each day. The tablets are dispersed by stirring in a glass of water or apple or orange juice (100 to 200 mL) until a line suspension is obtained. After the suspension has been swallowed, any residue must be resuspended in a small volume of water or juice and swallowed. The tablets must not be chewed or swallowed whole. Dispersion in carbonated drinks or milk is not recommended due to foaming and slow dispersion, respectively.</p>